Drug-coated balloons in below-the-knee arteries.
Vasa
; 51(4): 256-262, 2022 Jul.
Article
em En
| MEDLINE
| ID: mdl-35604329
ABSTRACT
Background:
The search for an optimal interventional treatment strategy in infrapopliteal peripheral artery disease remains in the focus of interest. Whether drug-coated balloons (DCB) might enhance interventional outcomes after crural interventions is a matter of debate, as studies yielded conflicting results on DCB safety and efficacy. Patients andmethods:
We analyzed a retrospective cohort of 75 infrapopliteal DCB interventions performed at our institution in 68 patients with peripheral artery disease in Rutherford category 3 to 6.Results:
Despite a high rate of long complex lesions and multi-vessel disease, freedom from clinically driven target lesions revascularization (TLR) after 365 days was 68%. After six months, healing or significant improvement of the ischemic ulcer was observed in 78% of cases. Accordingly, freedom from major amputation and death after 365 days was 82%. Freedom from major amputation and death was 76.2% of cases in patients with diabetes mellitus as opposed to 91.5% in patients without diabetes mellitus (p=0.049).Conclusions:
With this real-world analysis we would like to contribute to the ongoing discussion on the benefit and safety of DCB treatment in below-the-knee interventions.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fármacos Cardiovasculares
/
Angioplastia com Balão
/
Diabetes Mellitus
/
Doença Arterial Periférica
Tipo de estudo:
Observational_studies
Limite:
Humans
Idioma:
En
Revista:
Vasa
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Alemanha