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Recapitulation of endogenous 4R tau expression and formation of insoluble tau in directly reprogrammed human neurons.
Capano, Lucia S; Sato, Chihiro; Ficulle, Elena; Yu, Anan; Horie, Kanta; Kwon, Ji-Sun; Burbach, Kyle F; Barthélemy, Nicolas R; Fox, Susan G; Karch, Celeste M; Bateman, Randall J; Houlden, Henry; Morimoto, Richard I; Holtzman, David M; Duff, Karen E; Yoo, Andrew S.
Afiliação
  • Capano LS; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA; Center for Regenerative Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Program in Molecular and Cell Biology, Washington University School of Medicine, St. Louis, M
  • Sato C; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Ficulle E; UK Dementia Research Institute at University College London, London WC1E 6BT, UK.
  • Yu A; Department of Molecular Biosciences, Rice Institute for Biomedical Research, Northwestern University, Evanston, IL 60208, USA.
  • Horie K; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Kwon JS; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA; Program in Computational and Systems Biology, Washington University School of Medicine, St. Louis, Missouri, USA.
  • Burbach KF; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA; Program in Molecular Genetics and Genomics, Washington University School of Medicine, St. Louis, Missouri, USA.
  • Barthélemy NR; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Fox SG; Department of Molecular Biosciences, Rice Institute for Biomedical Research, Northwestern University, Evanston, IL 60208, USA.
  • Karch CM; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA; Hope Center for Neurological Disorders, Knight ADRC, St. Louis, MO 63110, USA; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Bateman RJ; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA; Hope Center for Neurological Disorders, Knight ADRC, St. Louis, MO 63110, USA.
  • Houlden H; UK Dementia Research Institute at University College London, London WC1E 6BT, UK.
  • Morimoto RI; Department of Molecular Biosciences, Rice Institute for Biomedical Research, Northwestern University, Evanston, IL 60208, USA.
  • Holtzman DM; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA; Hope Center for Neurological Disorders, Knight ADRC, St. Louis, MO 63110, USA.
  • Duff KE; UK Dementia Research Institute at University College London, London WC1E 6BT, UK. Electronic address: k.duff@ucl.ac.uk.
  • Yoo AS; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA; Center for Regenerative Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Hope Center for Neurological Disorders, Knight ADRC, St. Louis, MO 63110, USA. Electronic add
Cell Stem Cell ; 29(6): 918-932.e8, 2022 06 02.
Article em En | MEDLINE | ID: mdl-35659876
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tauopatias / MicroRNAs Limite: Adult / Humans Idioma: En Revista: Cell Stem Cell Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tauopatias / MicroRNAs Limite: Adult / Humans Idioma: En Revista: Cell Stem Cell Ano de publicação: 2022 Tipo de documento: Article