Anti-Inflammatory Mechanism of An Alkaloid Rutaecarpine in LTA-Stimulated RAW 264.7 Cells: Pivotal Role on NF-&#954;B and ERK/p38 Signaling Molecules.

Jayakumar, Thanasekaran; Yang, Chun-Ming; Yen, Ting-Lin; Hsu, Chia-Yuan; Sheu, Joen-Rong; Hsia, Chih-Wei; Manubolu, Manjunath; Huang, Wei-Chieh; Hsieh, Cheng-Ying; Hsia, Chih-Hsuan

Anti-Inflammatory Mechanism of An Alkaloid Rutaecarpine in LTA-Stimulated RAW 264.7 Cells: Pivotal Role on NF-κB and ERK/p38 Signaling Molecules.

Jayakumar, Thanasekaran; Yang, Chun-Ming; Yen, Ting-Lin; Hsu, Chia-Yuan; Sheu, Joen-Rong; Hsia, Chih-Wei; Manubolu, Manjunath; Huang, Wei-Chieh; Hsieh, Cheng-Ying; Hsia, Chih-Hsuan.

Afiliação

Jayakumar T; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Yang CM; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Yen TL; Department of Neurology, Chi Mei Medical Center, Tainan 710, Taiwan.
Hsu CY; Department of Medical Research, Cathay General Hospital, Taipei 106, Taiwan.
Sheu JR; Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Hsia CW; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Manubolu M; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Huang WC; Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Hsieh CY; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Hsia CH; Department of Evolution, Ecology and Organismal Biology, Ohio State University, Columbus, OH 43212, USA.

Int J Mol Sci ; 23(11)2022 May 24.

Article em En | MEDLINE | ID: mdl-35682568

Assuntos

MAP Quinases Reguladas por Sinal Extracelular; NF-kappa B; Animais; Anti-Inflamatórios/farmacologia; Ciclo-Oxigenase 2/metabolismo; MAP Quinases Reguladas por Sinal Extracelular/metabolismo; Alcaloides Indólicos/farmacologia; Lipopolissacarídeos/farmacologia; Camundongos; NF-kappa B/metabolismo; Óxido Nítrico/metabolismo; Óxido Nítrico Sintase Tipo II/metabolismo; Quinazolinas; Células RAW 264.7; Ácidos Teicoicos; Proteínas Quinases p38 Ativadas por Mitógeno/metabolismo

Palavras-chave

MAPK/NF-κB signaling pathways; anti-inflammation; inflammatory molecules; rutaecarpine

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: NF-kappa B / MAP Quinases Reguladas por Sinal Extracelular Limite: Animals Idioma: En Revista: Int J Mol Sci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Taiwan

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