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The Serological Sciences Network (SeroNet) for COVID-19: Depth and Breadth of Serology Assays and Plans for Assay Harmonization.
Karger, Amy B; Brien, James D; Christen, Jayne M; Dhakal, Santosh; Kemp, Troy J; Klein, Sabra L; Pinto, Ligia A; Premkumar, Lakshmanane; Roback, John D; Binder, Raquel A; Boehme, Karl W; Boppana, Suresh; Cordon-Cardo, Carlos; Crawford, James M; Daiss, John L; Dupuis, Alan P; Espino, Ana M; Firpo-Betancourt, Adolfo; Forconi, Catherine; Forrest, J Craig; Girardin, Roxie C; Granger, Douglas A; Granger, Steve W; Haddad, Natalie S; Heaney, Christopher D; Hunt, Danielle T; Kennedy, Joshua L; King, Christopher L; Krammer, Florian; Kruczynski, Kate; LaBaer, Joshua; Lee, F Eun-Hyung; Lee, William T; Liu, Shan-Lu; Lozanski, Gerard; Lucas, Todd; Mendu, Damodara Rao; Moormann, Ann M; Murugan, Vel; Okoye, Nkemakonam C; Pantoja, Petraleigh; Payne, Anne F; Park, Jin; Pinninti, Swetha; Pinto, Amelia K; Pisanic, Nora; Qiu, Ji; Sariol, Carlos A; Simon, Viviana; Song, Lusheng.
Afiliação
  • Karger AB; Department of Laboratory Medicine and Pathology, University of Minnesotagrid.17635.36, Minneapolis, Minnesota, USA.
  • Brien JD; Department of Molecular Microbiology & Immunology, Saint Louis Universitygrid.262962.b, St. Louis, Missouri, USA.
  • Christen JM; Frederick National Laboratory for Cancer Researchgrid.418021.e, Frederick, Maryland, USA.
  • Dhakal S; W. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
  • Kemp TJ; Frederick National Laboratory for Cancer Researchgrid.418021.e, Frederick, Maryland, USA.
  • Klein SL; W. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
  • Pinto LA; Frederick National Laboratory for Cancer Researchgrid.418021.e, Frederick, Maryland, USA.
  • Premkumar L; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, USA.
  • Roback JD; Department of Pathology and Laboratory Medicine, grid.471395.dgrid.189967.8Emory University School of Medicinegrid.471395.d, Atlanta, Georgia, USA.
  • Binder RA; Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.
  • Boehme KW; Department of Microbiology & Immunology, University of Arkansas for Medical Sciencesgrid.241054.6, Little Rock, Arkansas, USA.
  • Boppana S; Department of Pediatrics, University of Alabama at Birminghamgrid.265892.2, Birmingham, Alabama, USA.
  • Cordon-Cardo C; Department of Microbiology, University of Alabama at Birminghamgrid.265892.2, Birmingham, Alabama, USA.
  • Crawford JM; Department of Pathology, Icahn School of Medicine at Mount Sinaigrid.59734.3c, New York, New York, USA.
  • Daiss JL; Department of Pathology and Laboratory Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, USA.
  • Dupuis AP; MicroB-plex, Inc., Atlanta, Georgia, USA.
  • Espino AM; Wadsworth Centergrid.465543.5, New York State Department of Health, Albany, New York, USA.
  • Firpo-Betancourt A; Department of Microbiology and Medical Zoology, University of Puerto Rico-Medical Sciences Campus, San Juan, Puerto Rico, USA.
  • Forconi C; Department of Pathology, Icahn School of Medicine at Mount Sinaigrid.59734.3c, New York, New York, USA.
  • Forrest JC; Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.
  • Girardin RC; Department of Microbiology & Immunology, University of Arkansas for Medical Sciencesgrid.241054.6, Little Rock, Arkansas, USA.
  • Granger DA; Wadsworth Centergrid.465543.5, New York State Department of Health, Albany, New York, USA.
  • Granger SW; Salimetrics, LLC, Carlsbad, California, USA.
  • Haddad NS; Salimetrics, LLC, Carlsbad, California, USA.
  • Heaney CD; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, grid.471395.dgrid.189967.Emory University, Atlanta, Georgia, USA.
  • Hunt DT; Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
  • Kennedy JL; Wadsworth Centergrid.465543.5, New York State Department of Health, Albany, New York, USA.
  • King CL; Department of Pediatrics, University of Arkansas for Medical Sciencesgrid.241054.6, Little Rock, Arkansas, USA.
  • Krammer F; Department of Internal Medicine, University of Arkansas for Medical Sciencesgrid.241054.6, Little Rock, Arkansas, USA.
  • Kruczynski K; Arkansas Children's Research Institute, Little Rock, Arkansas, USA.
  • LaBaer J; Department of Pathology, Case Western Reserve School of Medicine, Cleveland, Ohio, USA.
  • Lee FE; Department of Microbiology, Icahn School of Medicine at Mount Sinaigrid.59734.3c, New York, New York, USA.
  • Lee WT; Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
  • Liu SL; Virginia G. Piper Center for Personalized Diagnostics, Arizona State University Biodesign Institute, Tempe, Arizona, USA.
  • Lozanski G; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, grid.471395.dgrid.189967.Emory University, Atlanta, Georgia, USA.
  • Lucas T; Wadsworth Centergrid.465543.5, New York State Department of Health, Albany, New York, USA.
  • Mendu DR; Department of Biomedical Sciences, School of Public Health, University at Albany, Albany, New York, USA.
  • Moormann AM; Center for Retrovirus Research, The Ohio State Universitygrid.261331.4, Columbus, Ohio, USA.
  • Murugan V; Department of Veterinary Biosciences, The Ohio State Universitygrid.261331.4, Columbus, Ohio, USA.
  • Okoye NC; Department of Microbial Infection and Immunity, The Ohio State Universitygrid.261331.4, Columbus, Ohio, USA.
  • Pantoja P; Viruses and Emerging Pathogens Program, Infectious Disease Institute, The Ohio State Universitygrid.261331.4, Columbus, Ohio, USA.
  • Payne AF; Department of Pathology, The Ohio State Universitygrid.261331.4 Medical Center, Columbus, Ohio, USA.
  • Park J; Division of Public Health, College of Human Medicine, Michigan State University, East Lansing, Michigan, USA.
  • Pinninti S; Department of Epidemiology, College of Human Medicine, Michigan State University, East Lansing, Michigan, USA.
  • Pinto AK; Department of Pathology, Icahn School of Medicine at Mount Sinaigrid.59734.3c, New York, New York, USA.
  • Pisanic N; Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.
  • Qiu J; Virginia G. Piper Center for Personalized Diagnostics, Arizona State University Biodesign Institute, Tempe, Arizona, USA.
  • Sariol CA; Department of Pathology and Laboratory Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, USA.
  • Simon V; Unit of Comparative Medicine, University of Puerto Rico-Medical Sciences Campus, San Juan, Puerto Rico, USA.
  • Song L; Wadsworth Centergrid.465543.5, New York State Department of Health, Albany, New York, USA.
mSphere ; 7(4): e0019322, 2022 08 31.
Article em En | MEDLINE | ID: mdl-35703544
ABSTRACT
In October 2020, the National Cancer Institute (NCI) Serological Sciences Network (SeroNet) was established to study the immune response to COVID-19, and "to develop, validate, improve, and implement serological testing and associated technologies" (https//www.cancer.gov/research/key-initiatives/covid-19/coronavirus-research-initiatives/serological-sciences-network). SeroNet is comprised of 25 participating research institutions partnering with the Frederick National Laboratory for Cancer Research (FNLCR) and the SeroNet Coordinating Center. Since its inception, SeroNet has supported collaborative development and sharing of COVID-19 serological assay procedures and has set forth plans for assay harmonization. To facilitate collaboration and procedure sharing, a detailed survey was sent to collate comprehensive assay details and performance metrics on COVID-19 serological assays within SeroNet. In addition, FNLCR established a protocol to calibrate SeroNet serological assays to reference standards, such as the U.S. severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serology standard reference material and first WHO international standard (IS) for anti-SARS-CoV-2 immunoglobulin (20/136), to facilitate harmonization of assay reporting units and cross-comparison of study data. SeroNet institutions reported development of a total of 27 enzyme-linked immunosorbent assay (ELISA) methods, 13 multiplex assays, and 9 neutralization assays and use of 12 different commercial serological methods. FNLCR developed a standardized protocol for SeroNet institutions to calibrate these diverse serological assays to reference standards. In conclusion, SeroNet institutions have established a diverse array of COVID-19 serological assays to study the immune response to SARS-CoV-2 and vaccines. Calibration of SeroNet serological assays to harmonize results reporting will facilitate future pooled data analyses and study cross-comparisons. IMPORTANCE SeroNet institutions have developed or implemented 61 diverse COVID-19 serological assays and are collaboratively working to harmonize these assays using reference materials to establish standardized reporting units. This will facilitate clinical interpretation of serology results and cross-comparison of research data.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: COVID-19 Tipo de estudo: Diagnostic_studies / Guideline Limite: Humans Idioma: En Revista: MSphere Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: COVID-19 Tipo de estudo: Diagnostic_studies / Guideline Limite: Humans Idioma: En Revista: MSphere Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos