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Nanoparticle-based oral formulation can surprise you with inferior in vivo absorption in humans.
Singhal, Mayank; Turunen, Elina; Ahtola-Sätilä, Tuula; Aspegren, John; Bratty, J Raymond; Fuhr, Rainard; Ojala, Krista; van Veen, Bert; Peltonen, Leena.
Afiliação
  • Singhal M; Orion Corporation, Orion Pharma, Research and Development, P.O. Box 65, 02101 Espoo, Finland; Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, P.O. Box 56, Viikinkaari 5 E, 00014 Helsinki, Finland.
  • Turunen E; Orion Corporation, Orion Pharma, Research and Development, P.O. Box 65, 02101 Espoo, Finland. Electronic address: elina.turunen@orionpharma.com.
  • Ahtola-Sätilä T; Orion Corporation, Orion Pharma, Research and Development, P.O. Box 65, 02101 Espoo, Finland.
  • Aspegren J; Orion Corporation, Orion Pharma, Research and Development, P.O. Box 65, 02101 Espoo, Finland.
  • Bratty JR; Orion Corporation, Orion Pharma, Research and Development, P.O. Box 65, 02101 Espoo, Finland.
  • Fuhr R; Parexel International GmbH, Campus DRK Kliniken Westend, House 18, Spandauer Damm 130, 14050 Berlin, Germany.
  • Ojala K; Orion Corporation, Orion Pharma, Research and Development, P.O. Box 65, 02101 Espoo, Finland.
  • van Veen B; Orion Corporation, Orion Pharma, Research and Development, P.O. Box 65, 02101 Espoo, Finland.
  • Peltonen L; Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, P.O. Box 56, Viikinkaari 5 E, 00014 Helsinki, Finland.
Eur J Pharm Biopharm ; 177: 91-99, 2022 Aug.
Article em En | MEDLINE | ID: mdl-35738336
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nanopartículas Limite: Humans Idioma: En Revista: Eur J Pharm Biopharm Assunto da revista: FARMACIA / FARMACOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Finlândia
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nanopartículas Limite: Humans Idioma: En Revista: Eur J Pharm Biopharm Assunto da revista: FARMACIA / FARMACOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Finlândia