In Vitro Cytotoxicity and Cytokine Production by Lipid-Substituted Low Molecular Weight Branched PEIs Used for Gene Delivery.

Meenakshi Sundaram, Daniel Nisakar; Plianwong, Samarwadee; Kc, Remant; Ostergaard, Hanne; Uludag, Hasan

Meenakshi Sundaram, Daniel Nisakar; Plianwong, Samarwadee; Kc, Remant; Ostergaard, Hanne; Uludag, Hasan.

Afiliação

Meenakshi Sundaram DN; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.
Plianwong S; Department of Chemical and Materials Engineering, University of Alberta, Edmonton, AB, Canada; Faculty of Pharmaceutical Sciences, Burapha University, Chonburi, Thailand.
Kc R; Department of Chemical and Materials Engineering, University of Alberta, Edmonton, AB, Canada.
Ostergaard H; Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, AB, Canada.
Uludag H; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada; Department of Chemical and Materials Engineering, University of Alberta, Edmonton, AB, Canada; Department of Biomedical Engineering, University of Alberta, Edmonton, AB, Canada. Electronic address: hasan.ul

Acta Biomater ; 148: 279-297, 2022 08.

Article em En | MEDLINE | ID: mdl-35738388

Assuntos

Hemólise; Polietilenoimina; Técnicas de Transferência de Genes; Humanos; Interleucina-6; Leucócitos Mononucleares; Ácido Linoleico; Peso Molecular; Plasmídeos; Polietilenoimina/efeitos adversos; Transfecção; Fator de Necrose Tumoral alfa/genética

Palavras-chave

Cytokine secretion; Hemolysis; Immune stimulation; Low molecular weight polyethyleneimine; Nucleic acid delivery

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polietilenoimina / Hemólise Limite: Humans Idioma: En Revista: Acta Biomater Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Canadá

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