"COVID toes": A true viral phenomenon or a diagnosis without a leg to stand on?
JAAD Int
; 9: 1-6, 2022 Dec.
Article
em En
| MEDLINE
| ID: mdl-35756912
"COVID toes" is the colloquial name of chilblain-like lesions thought to be a sequela of COVID-19 infection. Over two years and approximately 300 publications later, this association remains controversial. Here, we summarize key clinical, serological, biological, histological, and immunological evidence that supports and rejects this relationship and discuss alternate theories underlying the pathogenesis of chilblain-like lesions.
CBLL, chilblain-like lesion; COVID toes; COVID-19; EBV, Epstein-Barr virus; Epstein-Barr virus (EBV); IFN, interferon; Ig, immunoglobulin; RT-PCR, reverse transcriptase polymerase chain reaction; acral lesions; acro-ischemia; chilblain-like lesions (CBLL); chilblains; coronavirus; cutaneous vasculitis; factor V Leiden; humoral immunity; infection; interferon (IFN); lipoprotein A; pandemic; pernio; postacute sequelae of COVID-19 (PASC); pseudo-chilblains; skin of color; vaccine; virus
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Diagnostic_studies
Idioma:
En
Revista:
JAAD Int
Ano de publicação:
2022
Tipo de documento:
Article