HDAC inhibitor and proteasome inhibitor induce cleavage and exosome-mediated secretion of HSP90 in mouse pluripotent stem cells.

Choi, Jun-Kyu; Park, Sangkyu; Park, Jeong-A; Shin, Ha-Eun; Choi, Yeram; Lee, Younghee

Choi, Jun-Kyu; Park, Sangkyu; Park, Jeong-A; Shin, Ha-Eun; Choi, Yeram; Lee, Younghee.

Afiliação

Choi JK; Department of Biochemistry, College of Natural Sciences, Chungbuk National University, Cheongju, Chungbuk, 28644, South Korea; Biotechnology Research Institute, Chungbuk National University, Cheongju, Chungbuk, 28644, South Korea.
Park S; Department of Biochemistry, College of Natural Sciences, Chungbuk National University, Cheongju, Chungbuk, 28644, South Korea; Biotechnology Research Institute, Chungbuk National University, Cheongju, Chungbuk, 28644, South Korea.
Park JA; Department of Biochemistry, College of Natural Sciences, Chungbuk National University, Cheongju, Chungbuk, 28644, South Korea; Biotechnology Research Institute, Chungbuk National University, Cheongju, Chungbuk, 28644, South Korea.
Shin HE; Department of Biochemistry, College of Natural Sciences, Chungbuk National University, Cheongju, Chungbuk, 28644, South Korea.
Choi Y; Department of Biochemistry, College of Natural Sciences, Chungbuk National University, Cheongju, Chungbuk, 28644, South Korea.
Lee Y; Department of Biochemistry, College of Natural Sciences, Chungbuk National University, Cheongju, Chungbuk, 28644, South Korea; Biotechnology Research Institute, Chungbuk National University, Cheongju, Chungbuk, 28644, South Korea. Electronic address: yhl4177@cbnu.ac.kr.

Biochem Biophys Res Commun ; 620: 29-34, 2022 09 10.

Article em En | MEDLINE | ID: mdl-35777131

Assuntos

Exossomos; Células-Tronco Pluripotentes; Animais; Caspase 10/metabolismo; Exossomos/metabolismo; Proteínas de Choque Térmico HSP90/metabolismo; Inibidores de Histona Desacetilases/farmacologia; Camundongos; Células-Tronco Pluripotentes/metabolismo; Inibidores de Proteassoma/farmacologia; Espécies Reativas de Oxigênio/metabolismo

Palavras-chave

Exosome; Fas; HSP90 cleavage; Mouse ES cells; ROS; iPS cells

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Pluripotentes / Exossomos Limite: Animals Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Coréia do Sul

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