Humanized Anti-RGMa Antibody Treatment Promotes Repair of Blood-Spinal Cord Barrier Under Autoimmune Encephalomyelitis in Mice.

Hirata, Takeshi; Itokazu, Takahide; Sasaki, Atsushi; Sugihara, Fuminori; Yamashita, Toshihide

Hirata, Takeshi; Itokazu, Takahide; Sasaki, Atsushi; Sugihara, Fuminori; Yamashita, Toshihide.

Afiliação

Hirata T; Department of Neuro-Medical Science, Graduate School of Medicine, Osaka University, Suita, Japan.
Itokazu T; Sohyaku, Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Yokohama, Japan.
Sasaki A; Department of Neuro-Medical Science, Graduate School of Medicine, Osaka University, Suita, Japan.
Sugihara F; Department of Molecular Neuroscience, Graduate School of Medicine, Osaka University, Suita, Japan.
Yamashita T; Department of Neuro-Medical Science, Graduate School of Medicine, Osaka University, Suita, Japan.

Front Immunol ; 13: 870126, 2022.

Article em En | MEDLINE | ID: mdl-35784362

Assuntos

Encefalomielite Autoimune Experimental; Encefalomielite; Esclerose Múltipla; Animais; Encefalomielite/patologia; Células Endoteliais/patologia; Proteínas Ligadas por GPI; Camundongos; Proteínas do Tecido Nervoso; Medula Espinal/patologia

Palavras-chave

EAE; blood-brain barrier; blood-spinal cord barrier; magnetic resonance imaging; multiple sclerosis; neuropathology; rgma; vascular pathology

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encefalomielite / Encefalomielite Autoimune Experimental / Esclerose Múltipla Tipo de estudo: Guideline Limite: Animals Idioma: En Revista: Front Immunol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Japão

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