The emerging coloprotective effect of sildenafil against ulcerative colitis in rats via exerting counterbalance between NF-&#954;B signaling and Nrf-2/HO-1 pathway.

El-Tanbouly, Ghada S; Abdelrahman, Rehab S

The emerging coloprotective effect of sildenafil against ulcerative colitis in rats via exerting counterbalance between NF-κB signaling and Nrf-2/HO-1 pathway.

El-Tanbouly, Ghada S; Abdelrahman, Rehab S.

Afiliação

El-Tanbouly GS; Department of Pharmacology, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, 11152, Egypt. ghada_samy83@yahoo.com.
Abdelrahman RS; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt.

Inflammopharmacology ; 30(4): 1351-1362, 2022 Aug.

Article em En | MEDLINE | ID: mdl-35834151

Assuntos

Colite Ulcerativa; Ácido Acético/farmacologia; Animais; Colite Ulcerativa/induzido quimicamente; Colite Ulcerativa/tratamento farmacológico; Colite Ulcerativa/metabolismo; Colo; Dexametasona/farmacologia; NF-kappa B/metabolismo; Ratos; Citrato de Sildenafila/efeitos adversos; Citrato de Sildenafila/metabolismo; Fator de Necrose Tumoral alfa/metabolismo

Palavras-chave

Acetic acid; HO-1; NF-κB p65; Nrf-2; Sildenafil; Ulcerative colitis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colite Ulcerativa Limite: Animals Idioma: En Revista: Inflammopharmacology Assunto da revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Egito

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