Epigenomics of conventional type-I dendritic cells depicted preferential control of TLR9 versus TLR3 response by NCoR1 through differential IRF3 activation.

Mishra, Gyan Prakash; Jha, Atimukta; Ahad, Abdul; Sen, Kaushik; Sen, Aishwarya; Podder, Sreeparna; Prusty, Subhasish; Biswas, Viplov Kumar; Gupta, Bhawna; Raghav, Sunil Kumar

Mishra, Gyan Prakash; Jha, Atimukta; Ahad, Abdul; Sen, Kaushik; Sen, Aishwarya; Podder, Sreeparna; Prusty, Subhasish; Biswas, Viplov Kumar; Gupta, Bhawna; Raghav, Sunil Kumar.

Afiliação

Mishra GP; Immuno-Genomics and Systems Biology Laboratory, Institute of Life Sciences (ILS), Bhubaneswar, Odisha, 751023, India.
Jha A; School of Biotechnology, Kalinga Institute of Industrial Technology (KIIT), Bhubaneswar, Odisha, 751024, India.
Ahad A; Immuno-Genomics and Systems Biology Laboratory, Institute of Life Sciences (ILS), Bhubaneswar, Odisha, 751023, India.
Sen K; Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
Sen A; Immuno-Genomics and Systems Biology Laboratory, Institute of Life Sciences (ILS), Bhubaneswar, Odisha, 751023, India.
Podder S; Immuno-Genomics and Systems Biology Laboratory, Institute of Life Sciences (ILS), Bhubaneswar, Odisha, 751023, India.
Prusty S; Regional Centre for Biotechnology, Faridabad, Haryana, 121001, India.
Biswas VK; Immuno-Genomics and Systems Biology Laboratory, Institute of Life Sciences (ILS), Bhubaneswar, Odisha, 751023, India.
Gupta B; Regional Centre for Biotechnology, Faridabad, Haryana, 121001, India.
Raghav SK; Immuno-Genomics and Systems Biology Laboratory, Institute of Life Sciences (ILS), Bhubaneswar, Odisha, 751023, India.

Cell Mol Life Sci ; 79(8): 429, 2022 Jul 18.

Article em En | MEDLINE | ID: mdl-35849243

Assuntos

Receptor 3 Toll-Like; Receptor Toll-Like 9; Animais; Antivirais; Linfócitos T CD8-Positivos; Células Dendríticas/metabolismo; Epigenômica; Fator Regulador 3 de Interferon/genética; Fator Regulador 3 de Interferon/metabolismo; Camundongos; Correpressor 1 de Receptor Nuclear/genética; Correpressor 1 de Receptor Nuclear/metabolismo; Transdução de Sinais; Receptor 3 Toll-Like/genética; Receptor 3 Toll-Like/metabolismo; Receptor Toll-Like 9/genética; Receptor Toll-Like 9/metabolismo; Receptores Toll-Like

Palavras-chave

Dendritic cells; Enhancer activity; Immune response; Multi-omics data analysis (RNA-seq and ChIP-seq); NCoR1; TLR activation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptor Toll-Like 9 / Receptor 3 Toll-Like Limite: Animals Idioma: En Revista: Cell Mol Life Sci Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Índia

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