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Comprehensive genomic and epigenomic analysis in cancer of unknown primary guides molecularly-informed therapies despite heterogeneity.
Möhrmann, Lino; Werner, Maximilian; Oles, Malgorzata; Mock, Andreas; Uhrig, Sebastian; Jahn, Arne; Kreutzfeldt, Simon; Fröhlich, Martina; Hutter, Barbara; Paramasivam, Nagarajan; Richter, Daniela; Beck, Katja; Winter, Ulrike; Pfütze, Katrin; Heilig, Christoph E; Teleanu, Veronica; Lipka, Daniel B; Zapatka, Marc; Hanf, Dorothea; List, Catrin; Allgäuer, Michael; Penzel, Roland; Rüter, Gina; Jelas, Ivan; Hamacher, Rainer; Falkenhorst, Johanna; Wagner, Sebastian; Brandts, Christian H; Boerries, Melanie; Illert, Anna L; Metzeler, Klaus H; Westphalen, C Benedikt; Desuki, Alexander; Kindler, Thomas; Folprecht, Gunnar; Weichert, Wilko; Brors, Benedikt; Stenzinger, Albrecht; Schröck, Evelin; Hübschmann, Daniel; Horak, Peter; Heining, Christoph; Fröhling, Stefan; Glimm, Hanno.
Afiliação
  • Möhrmann L; Department of Translational Medical Oncology, National Center for Tumor Diseases (NCT) Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Werner M; Center for Personalized Oncology, NCT Dresden and University Hospital Carl Gustav Carus, Faculty of Medicine and Technische Universität Dresden, Dresden, Germany.
  • Oles M; German Cancer Consortium (DKTK), Dresden, Germany.
  • Mock A; Department of Translational Medical Oncology, National Center for Tumor Diseases (NCT) Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Uhrig S; Computational Oncology Group, NCT Heidelberg and DKFZ, Heidelberg, Germany.
  • Jahn A; Department of Translational Medical Oncology, NCT Heidelberg and DKFZ, Heidelberg, Germany.
  • Kreutzfeldt S; Department of Translational Medical Oncology, NCT Heidelberg and DKFZ, Heidelberg, Germany.
  • Fröhlich M; Department of Medical Oncology, NCT Heidelberg and Heidelberg University Hospital, Heidelberg, Germany.
  • Hutter B; Computational Oncology Group, NCT Heidelberg and DKFZ, Heidelberg, Germany.
  • Paramasivam N; Molecular Precision Oncology Program, NCT Heidelberg, Heidelberg, Germany.
  • Richter D; Center for Personalized Oncology, NCT Dresden and University Hospital Carl Gustav Carus, Faculty of Medicine and Technische Universität Dresden, Dresden, Germany.
  • Beck K; German Cancer Consortium (DKTK), Dresden, Germany.
  • Winter U; Institute for Clinical Genetics, University Hospital Carl Gustav Carus Dresden, Technische Universität Dresden, Dresden, Germany.
  • Pfütze K; Department of Translational Medical Oncology, NCT Heidelberg and DKFZ, Heidelberg, Germany.
  • Heilig CE; Computational Oncology Group, NCT Heidelberg and DKFZ, Heidelberg, Germany.
  • Teleanu V; Molecular Precision Oncology Program, NCT Heidelberg, Heidelberg, Germany.
  • Lipka DB; Computational Oncology Group, NCT Heidelberg and DKFZ, Heidelberg, Germany.
  • Zapatka M; Molecular Precision Oncology Program, NCT Heidelberg, Heidelberg, Germany.
  • Hanf D; Computational Oncology Group, NCT Heidelberg and DKFZ, Heidelberg, Germany.
  • List C; Molecular Precision Oncology Program, NCT Heidelberg, Heidelberg, Germany.
  • Allgäuer M; Department of Translational Medical Oncology, National Center for Tumor Diseases (NCT) Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Penzel R; German Cancer Consortium (DKTK), Dresden, Germany.
  • Rüter G; Molecular Precision Oncology Program, NCT Heidelberg, Heidelberg, Germany.
  • Jelas I; Molecular Precision Oncology Program, NCT Heidelberg, Heidelberg, Germany.
  • Hamacher R; Molecular Precision Oncology Program, NCT Heidelberg, Heidelberg, Germany.
  • Falkenhorst J; Department of Translational Medical Oncology, NCT Heidelberg and DKFZ, Heidelberg, Germany.
  • Wagner S; Department of Translational Medical Oncology, NCT Heidelberg and DKFZ, Heidelberg, Germany.
  • Brandts CH; Department of Translational Medical Oncology, NCT Heidelberg and DKFZ, Heidelberg, Germany.
  • Boerries M; Section Translational Cancer Epigenomics, Department of Translational Medical Oncology, NCT Heidelberg and DKFZ, Heidelberg, Germany.
  • Illert AL; Division of Molecular Genetics, DKFZ, Heidelberg, Germany.
  • Metzeler KH; Department of Translational Medical Oncology, National Center for Tumor Diseases (NCT) Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Westphalen CB; Center for Personalized Oncology, NCT Dresden and University Hospital Carl Gustav Carus, Faculty of Medicine and Technische Universität Dresden, Dresden, Germany.
  • Desuki A; Department of Translational Medical Oncology, National Center for Tumor Diseases (NCT) Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Kindler T; Center for Personalized Oncology, NCT Dresden and University Hospital Carl Gustav Carus, Faculty of Medicine and Technische Universität Dresden, Dresden, Germany.
  • Folprecht G; Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
  • Weichert W; Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
  • Brors B; Charité Comprehensive Cancer Center, Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
  • Stenzinger A; Charité Comprehensive Cancer Center, Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
  • Schröck E; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Essen, Germany.
  • Hübschmann D; DKTK, Essen, Germany.
  • Horak P; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Essen, Germany.
  • Heining C; DKTK, Essen, Germany.
  • Fröhling S; Department of Medicine 2, Hematology/Oncology, Goethe University, Frankfurt, Germany.
  • Glimm H; DKTK, Frankfurt, Germany.
Nat Commun ; 13(1): 4485, 2022 08 02.
Article em En | MEDLINE | ID: mdl-35918329
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Primárias Desconhecidas Tipo de estudo: Guideline Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Primárias Desconhecidas Tipo de estudo: Guideline Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha