TBK1-mTOR Signaling Attenuates Obesity-Linked Hyperglycemia and Insulin Resistance.

Bodur, Cagri; Kazyken, Dubek; Huang, Kezhen; Tooley, Aaron Seth; Cho, Kae Won; Barnes, Tammy M; Lumeng, Carey N; Myers, Martin G; Fingar, Diane C

Bodur, Cagri; Kazyken, Dubek; Huang, Kezhen; Tooley, Aaron Seth; Cho, Kae Won; Barnes, Tammy M; Lumeng, Carey N; Myers, Martin G; Fingar, Diane C.

Afiliação

Bodur C; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI.
Kazyken D; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI.
Huang K; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI.
Tooley AS; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI.
Cho KW; Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, MI.
Barnes TM; Department of Internal Medicine, Division of Metabolism, Endocrinology, and Diabetes, University of Michigan Medical School, Ann Arbor, MI.
Lumeng CN; Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, MI.
Myers MG; Department of Internal Medicine, Division of Metabolism, Endocrinology, and Diabetes, University of Michigan Medical School, Ann Arbor, MI.
Fingar DC; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI.

Diabetes ; 71(11): 2297-2312, 2022 11 01.

Article em En | MEDLINE | ID: mdl-35983955

Assuntos

Hiperglicemia; Resistência à Insulina; Camundongos; Animais; Resistência à Insulina/genética; Complexos Multiproteicos/metabolismo; Serina-Treonina Quinases TOR/metabolismo; Alvo Mecanístico do Complexo 1 de Rapamicina/metabolismo; Alvo Mecanístico do Complexo 2 de Rapamicina; Sirolimo/farmacologia; Insulina/metabolismo; Obesidade/genética; Camundongos Obesos; Hiperglicemia/genética; Glucose; Proteínas Serina-Treonina Quinases/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Hiperglicemia Limite: Animals Idioma: En Revista: Diabetes Ano de publicação: 2022 Tipo de documento: Article

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