Orbital solitary fibrous tumours: clinicopathological characteristics and recurrence prediction.
Graefes Arch Clin Exp Ophthalmol
; 261(1): 223-231, 2023 Jan.
Article
em En
| MEDLINE
| ID: mdl-36029306
ABSTRACT
BACKGROUND:
SFTs are thought to have an unpredictable clinical course and currently have no recognized prognostic criterion. Our study aimed to determine the relationship between clinicopathological characteristics and the prognosis of patients with orbital SFTs.METHODS:
The clinicopathological features of these patients were extracted from clinical records. The relationships between these features and prognosis were analysed.RESULTS:
The positive rates of CD34, CD99, Blc2, and STAT6 expression were 90.3%, 90.3%, 83.9%, and 100%, respectively. The tumour recurrence rate was 38.7%. A higher recurrence rate was observed in patients with Ki67 index ≥ 5 (56.25% vs. 20%, P = 0.038).CONCLUSION:
A Ki67 index ≥ 5 was an effective parameter for predicting tumour recurrence of orbital SFTs. Close follow-up is needed for these patients.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tumores Fibrosos Solitários
/
Febre Grave com Síndrome de Trombocitopenia
/
Hemangiopericitoma
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Graefes Arch Clin Exp Ophthalmol
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
China