FOXO1 represses MCL1 transcription to regulate the function of vascular smooth muscle cells in intracranial aneurysm.

Huang, Jinqing; Hong, Lang; Shen, Binghua; Zhou, Yunying; Lan, Jianyun; Peng, Ying

Huang, Jinqing; Hong, Lang; Shen, Binghua; Zhou, Yunying; Lan, Jianyun; Peng, Ying.

Afiliação

Huang J; Department of Neurosurgery, Ganzhou People's Hospital (the Affiliated Ganzhou Hospital of Nanchang University), Ganzhou, 341000, Jiangxi, People's Republic of China.
Hong L; Department of Cardiology, Jiangxi Provincial People's Hospital (the first Affiliated Hospital of Nanchang Medical College), No.92 Aiguo Rd, Donghu District, Nanchang, 330006, Jiangxi, People's Republic of China.
Shen B; Department of Rheumatology and Immunology, Jiangxi Provincial People's Hospital (the first Affiliated Hospital of Nanchang Medical College), Nanchang, 330006, Jiangxi, People's Republic of China.
Zhou Y; Department of Cardiology, Jiangxi Provincial People's Hospital (the first Affiliated Hospital of Nanchang Medical College), No.92 Aiguo Rd, Donghu District, Nanchang, 330006, Jiangxi, People's Republic of China.
Lan J; Department of Cardiology, Jiangxi Provincial People's Hospital (the first Affiliated Hospital of Nanchang Medical College), No.92 Aiguo Rd, Donghu District, Nanchang, 330006, Jiangxi, People's Republic of China.
Peng Y; Department of Cardiology, Jiangxi Provincial People's Hospital (the first Affiliated Hospital of Nanchang Medical College), No.92 Aiguo Rd, Donghu District, Nanchang, 330006, Jiangxi, People's Republic of China. pengying198212@163.com.

Exp Brain Res ; 240(11): 2861-2870, 2022 Nov.

Article em En | MEDLINE | ID: mdl-36104628

Assuntos

Aneurisma Intracraniano; MicroRNAs; Humanos; Músculo Liso Vascular/metabolismo; Músculo Liso Vascular/patologia; Aneurisma Intracraniano/genética; Aneurisma Intracraniano/metabolismo; Aneurisma Intracraniano/patologia; Caspase 3/metabolismo; Proteína de Sequência 1 de Leucemia de Células Mieloides/genética; Proteína de Sequência 1 de Leucemia de Células Mieloides/metabolismo; Fator de Necrose Tumoral alfa/metabolismo; Interleucina-6/metabolismo; Sincalida/metabolismo; Apoptose/genética; Citocinas/metabolismo; RNA Mensageiro/metabolismo; Luciferases/metabolismo; MicroRNAs/genética; Proteína Forkhead Box O1/genética; Proteína Forkhead Box O1/metabolismo

Palavras-chave

Apoptosis; FOXO1; Inflammation; Intracranial aneurysm; MCL1; Proliferation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aneurisma Intracraniano / MicroRNAs Limite: Humans Idioma: En Revista: Exp Brain Res Ano de publicação: 2022 Tipo de documento: Article

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