Your browser doesn't support javascript.
loading
[Association of BMI with acute exacerbation in mild to moderate chronic obstructive pulmonary disease patients in community: a prospective study].
Ruan, X N; Xu, Q; Wu, K; Hou, S S; Wang, X N; Zhou, X; Li, Z T; Ke, J Z; Liu, X L; Chen, X D; Liu, Q P; Lin, T; Fu, C W; Wang, N.
Afiliação
  • Ruan XN; Pudong New District Center for Disease Control and Prevention of Shanghai, Shanghai 200136,China Pudong Preventive Medicine Research Institute,Fudan University, Shanghai 200136, China.
  • Xu Q; Pudong Preventive Medicine Research Institute,Fudan University, Shanghai 200136, China Department of Epidemiology, School of Public Health, Fudan University, Shanghai 200032, China.
  • Wu K; Pudong New District Center for Disease Control and Prevention of Shanghai, Shanghai 200136,China Pudong Preventive Medicine Research Institute,Fudan University, Shanghai 200136, China.
  • Hou SS; Pudong Preventive Medicine Research Institute,Fudan University, Shanghai 200136, China Department of Epidemiology, School of Public Health, Fudan University, Shanghai 200032, China.
  • Wang XN; Pudong New District Center for Disease Control and Prevention of Shanghai, Shanghai 200136,China Pudong Preventive Medicine Research Institute,Fudan University, Shanghai 200136, China.
  • Zhou X; Pudong New District Center for Disease Control and Prevention of Shanghai, Shanghai 200136,China Pudong Preventive Medicine Research Institute,Fudan University, Shanghai 200136, China.
  • Li ZT; Pudong New District Center for Disease Control and Prevention of Shanghai, Shanghai 200136,China Pudong Preventive Medicine Research Institute,Fudan University, Shanghai 200136, China.
  • Ke JZ; Pudong New District Center for Disease Control and Prevention of Shanghai, Shanghai 200136,China Pudong Preventive Medicine Research Institute,Fudan University, Shanghai 200136, China.
  • Liu XL; Pudong New District Center for Disease Control and Prevention of Shanghai, Shanghai 200136,China Pudong Preventive Medicine Research Institute,Fudan University, Shanghai 200136, China.
  • Chen XD; Pudong New District Center for Disease Control and Prevention of Shanghai, Shanghai 200136,China Pudong Preventive Medicine Research Institute,Fudan University, Shanghai 200136, China.
  • Liu QP; Pudong New District Center for Disease Control and Prevention of Shanghai, Shanghai 200136,China Pudong Preventive Medicine Research Institute,Fudan University, Shanghai 200136, China.
  • Lin T; Pudong New District Center for Disease Control and Prevention of Shanghai, Shanghai 200136,China Pudong Preventive Medicine Research Institute,Fudan University, Shanghai 200136, China.
  • Fu CW; Pudong Preventive Medicine Research Institute,Fudan University, Shanghai 200136, China Department of Epidemiology, School of Public Health, Fudan University, Shanghai 200032, China.
  • Wang N; Pudong Preventive Medicine Research Institute,Fudan University, Shanghai 200136, China Department of Epidemiology, School of Public Health, Fudan University, Shanghai 200032, China.
Zhonghua Liu Xing Bing Xue Za Zhi ; 43(9): 1441-1447, 2022 Sep 10.
Article em Zh | MEDLINE | ID: mdl-36117352
ABSTRACT

Objective:

BMI may play a protective role in reducing the mortality rate of patients with chronic obstructive pulmonary disease (COPD), but its effect on acute exacerbation of COPD remain unclear.

Methods:

Subjects were selected from the COPD patients registration system established in 2014 in Pudong new district, Shanghai. COPD patients from 8 communities were selected by cluster sampling and follow up was conducted prospectively for 18 months. Basic information and BMI were obtained from baseline survey, and acute exacerbations were collected during follow-up. The association between BMI and risk of acute exacerbation was evaluated by using multiple negative binomial regression.

Results:

Among 328 community COPD patients, 295 who completed the follow up were included in the analysis, in whom 96.3% (284/295) were mild COPD patients. During the follow-up, 11.1% (33/295) of the patients reported acute exacerbation. The results of multiple negative binomial regression suggested that, the risk for acute exacerbation decreased with the increase of BMI (IRR=0.85, 95%CI0.73-0.98), overweight patients with BMI ≥25.0 kg/m2 (IRR=0.36, 95%CI0.13-0.91) or moderate BMI (T2 vs. T1, IRR=0.31, 95%CI0.11-0.77) had lower risk for acute exacerbation compared with the patients with normal or low BMI. BMI had a linear correlation with the risk of acute exacerbation.

Conclusion:

The risk for acute exacerbation in patients with mild or moderate COPD in communities decreased with the increase of BMI, and being overweight might be a protective factor for the acute exacerbation of COPD.
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença Pulmonar Obstrutiva Crônica / Sobrepeso Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Humans País/Região como assunto: Asia Idioma: Zh Revista: Zhonghua Liu Xing Bing Xue Za Zhi Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença Pulmonar Obstrutiva Crônica / Sobrepeso Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Humans País/Região como assunto: Asia Idioma: Zh Revista: Zhonghua Liu Xing Bing Xue Za Zhi Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China