Isolation of Chalcomoracin as a Potential &#945;-Glycosidase Inhibitor from Mulberry Leaves and Its Binding Mechanism.

Liu, Yang; Zhou, Xue; Zhou, Dan; Jian, Yongxing; Jia, Jingfu; Ge, Fahuan

Isolation of Chalcomoracin as a Potential α-Glycosidase Inhibitor from Mulberry Leaves and Its Binding Mechanism.

Liu, Yang; Zhou, Xue; Zhou, Dan; Jian, Yongxing; Jia, Jingfu; Ge, Fahuan.

Afiliação

Liu Y; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Zhou X; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Zhou D; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Jian Y; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Jia J; Chemistry and Chemical Engineering Guangdong Laboratory, Shantou 515000, China.
Ge F; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.

Molecules ; 27(18)2022 Sep 06.

Article em En | MEDLINE | ID: mdl-36144478

Assuntos

Diabetes Mellitus; Morus; Acarbose/análise; Acarbose/farmacologia; Benzofuranos; Glicogênio/metabolismo; Inibidores de Glicosídeo Hidrolases/química; Humanos; Hipoglicemiantes/metabolismo; Simulação de Acoplamento Molecular; Morus/química; Folhas de Planta/química; Amido/metabolismo; alfa-Glucosidases/metabolismo

Palavras-chave

chalcomoracin; enzymatic kinetics; molecular docking; mulberry leaf; α-glucosidase inhibitor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Morus / Diabetes Mellitus Limite: Humans Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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