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Pharmacological mTOR-inhibition facilitates clearance of AD-related tau aggregates in the mouse brain.
Morawe, Martina P; Liao, Fan; Amberg, Willi; van Bergeijk, Jeroen; Chang, Rui; Gulino, Mary; Hamilton, Caitlin; Hoft, Carolin; Lumpkin, Casey; Mastis, Bryan; McGlame, Emily; Nuber, Judith; Plaas, Christian; Ravikumar, Brinda; Roy, Kaushambi; Schanzenbächer, Marion; Tierno, Joseph; Lakics, Viktor; Dellovade, Tammy; Townsend, Matthew.
Afiliação
  • Morawe MP; AbbVie Deutschland GmbH & Co. KG, Neuroscience Research, Knollstrasse, 67061, Ludwigshafen, Germany. Electronic address: martina.morawe@abbvie.com.
  • Liao F; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA.
  • Amberg W; AbbVie Deutschland GmbH & Co. KG, Neuroscience Research, Knollstrasse, 67061, Ludwigshafen, Germany.
  • van Bergeijk J; AbbVie Deutschland GmbH & Co. KG, Neuroscience Research, Knollstrasse, 67061, Ludwigshafen, Germany.
  • Chang R; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA.
  • Gulino M; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA.
  • Hamilton C; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA.
  • Hoft C; AbbVie Deutschland GmbH & Co. KG, Drug Metabolism & Pharmacokinetics, Knollstrasse, 67061, Ludwigshafen, Germany.
  • Lumpkin C; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA.
  • Mastis B; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA.
  • McGlame E; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA.
  • Nuber J; AbbVie Deutschland GmbH & Co. KG, Neuroscience Research, Knollstrasse, 67061, Ludwigshafen, Germany.
  • Plaas C; AbbVie Deutschland GmbH & Co. KG, Neuroscience Research, Knollstrasse, 67061, Ludwigshafen, Germany.
  • Ravikumar B; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA.
  • Roy K; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA.
  • Schanzenbächer M; AbbVie Deutschland GmbH & Co. KG, Neuroscience Research, Knollstrasse, 67061, Ludwigshafen, Germany.
  • Tierno J; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA.
  • Lakics V; AbbVie Deutschland GmbH & Co. KG, Neuroscience Research, Knollstrasse, 67061, Ludwigshafen, Germany.
  • Dellovade T; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA.
  • Townsend M; AbbVie, Cambridge Research Center, 200 Sidney Street, Cambridge, MA, 02139, USA. Electronic address: matt.townsend@abbvie.com.
Eur J Pharmacol ; 934: 175301, 2022 Nov 05.
Article em En | MEDLINE | ID: mdl-36191631
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Alzheimer Limite: Animals Idioma: En Revista: Eur J Pharmacol Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Alzheimer Limite: Animals Idioma: En Revista: Eur J Pharmacol Ano de publicação: 2022 Tipo de documento: Article