Electrochemical Palladium-Catalyzed Oxidative Carbonylation-Cyclization of Enallenols.

Zhang, Jianwei; Das, Biswanath; Verho, Oscar; Bäckvall, Jan-E

Zhang, Jianwei; Das, Biswanath; Verho, Oscar; Bäckvall, Jan-E.

Afiliação

Zhang J; Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, 10691, Stockholm, Sweden.
Das B; Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, 10691, Stockholm, Sweden.
Verho O; Department of Medicinal Chemistry, Uppsala Biomedical Center, BMC, Uppsala University, 75236, Uppsala, Sweden.
Bäckvall JE; Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, 10691, Stockholm, Sweden.

Angew Chem Int Ed Engl ; 61(49): e202212131, 2022 Dec 05.

Article em En | MEDLINE | ID: mdl-36222322

ABSTRACT

ABSTRACT

Herein, we report an electrochemical oxidative palladium-catalyzed carbonylation-carbocyclization of enallenols to afford Î³-lactones and spirolactones, which proceeds with excellent chemoselectivity. Interestingly, electrocatalysis was found to have an accelerating effect on the rate of the tandem process, leading to a more efficient reaction than that under chemical redox conditions.

Palavras-chave

Anodic Oxidation; Electrocatalysis; Enallenol; Palladium; Undivided Cell

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Angew Chem Int Ed Engl Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Suécia

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