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Mesenchymal stem cells-derived HIF-1α-overexpressed extracellular vesicles ameliorate hypoxia-induced pancreatic ß cell apoptosis and senescence through activating YTHDF1-mediated protective autophagy.
Fang, Jiali; Chen, Zheng; Lai, Xingqiang; Yin, Wei; Guo, Yuhe; Zhang, Weiting; Ma, Junjie; Li, Guanghui; Zhang, Lei.
Afiliação
  • Fang J; Department of Organ Transplantation, The Second Affiliated Hospital of Guangzhou Medical University, Yayun South Road No. 63, Guangzhou 510000, Guangdong, China. Electronic address: 2013682011@gzhmu.edu.cn.
  • Chen Z; Department of Organ Transplantation, The Second Affiliated Hospital of Guangzhou Medical University, Yayun South Road No. 63, Guangzhou 510000, Guangdong, China. Electronic address: 2012682015@gzhmu.edu.cn.
  • Lai X; Department of Organ Transplantation, The Second Affiliated Hospital of Guangzhou Medical University, Yayun South Road No. 63, Guangzhou 510000, Guangdong, China.
  • Yin W; Department of Organ Transplantation, The Second Affiliated Hospital of Guangzhou Medical University, Yayun South Road No. 63, Guangzhou 510000, Guangdong, China.
  • Guo Y; Department of Organ Transplantation, The Second Affiliated Hospital of Guangzhou Medical University, Yayun South Road No. 63, Guangzhou 510000, Guangdong, China.
  • Zhang W; Department of Organ Transplantation, The Second Affiliated Hospital of Guangzhou Medical University, Yayun South Road No. 63, Guangzhou 510000, Guangdong, China.
  • Ma J; Department of Organ Transplantation, The Second Affiliated Hospital of Guangzhou Medical University, Yayun South Road No. 63, Guangzhou 510000, Guangdong, China.
  • Li G; Department of Organ Transplantation, The Second Affiliated Hospital of Guangzhou Medical University, Yayun South Road No. 63, Guangzhou 510000, Guangdong, China.
  • Zhang L; Department of Organ Transplantation, The Second Affiliated Hospital of Guangzhou Medical University, Yayun South Road No. 63, Guangzhou 510000, Guangdong, China.
Bioorg Chem ; 129: 106194, 2022 12.
Article em En | MEDLINE | ID: mdl-36244321
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Secretoras de Insulina / Células-Tronco Mesenquimais / Vesículas Extracelulares Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Secretoras de Insulina / Células-Tronco Mesenquimais / Vesículas Extracelulares Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2022 Tipo de documento: Article