Inhibition of glutamatergic neurons in layer II/III of the medial prefrontal cortex alleviates paclitaxel-induced neuropathic pain and anxiety.

Cao, Jing; Liu, Xin; Liu, Jia-Xin; Zhao, Shuang; Guo, Yue-Xian; Wang, Gui-Ying; Wang, Xiu-Li

Cao, Jing; Liu, Xin; Liu, Jia-Xin; Zhao, Shuang; Guo, Yue-Xian; Wang, Gui-Ying; Wang, Xiu-Li.

Afiliação

Cao J; Department of Anesthesiology, The Third Hospital of Hebei Medical University, Shijiazhuang, China. Electronic address: caojing782x@163.com.
Liu X; Department of Anesthesiology, The Third Hospital of Hebei Medical University, Shijiazhuang, China. Electronic address: 1536149525@qq.com.
Liu JX; Department of Anesthesiology, The Third Hospital of Hebei Medical University, Shijiazhuang, China. Electronic address: liujiaxin1111@qq.com.
Zhao S; Department of Anesthesiology, The Third Hospital of Hebei Medical University, Shijiazhuang, China. Electronic address: zhaoshuang810924@163.com.
Guo YX; Department of Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, China. Electronic address: guoyuexian@aliyun.com.
Wang GY; Department of Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, China. Electronic address: wangguiying@hebmu.edu.cn.
Wang XL; Department of Anesthesiology, The Third Hospital of Hebei Medical University, Shijiazhuang, China. Electronic address: wangxl311@126.com.

Eur J Pharmacol ; 936: 175351, 2022 Dec 05.

Article em En | MEDLINE | ID: mdl-36309050

Assuntos

Proteína Quinase Tipo 2 Dependente de Cálcio-Calmodulina; Neuralgia; Animais; Camundongos; Ansiedade/induzido quimicamente; Ansiedade/tratamento farmacológico; Ansiedade/metabolismo; Cálcio/metabolismo; Proteína Quinase Tipo 2 Dependente de Cálcio-Calmodulina/metabolismo; Neuralgia/induzido quimicamente; Neuralgia/metabolismo; Neurônios/metabolismo; Paclitaxel/metabolismo; Córtex Pré-Frontal/metabolismo

Palavras-chave

Anxiety; CaMKII; Chemotherapy-induced peripheral neuropathy; Medial prefrontal cortex; Paclitaxel

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Quinase Tipo 2 Dependente de Cálcio-Calmodulina / Neuralgia Limite: Animals Idioma: En Revista: Eur J Pharmacol Ano de publicação: 2022 Tipo de documento: Article

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