Chemotherapy induces feedback up-regulation of CD44v6 in colorectal cancer initiating cells through <i>ß</i>-catenin/MDR1 signaling to sustain chemoresistance.

Ghatak, Shibnath; Hascall, Vincent C; Karamanos, Nikos; Markwald, Roger R; Misra, Suniti

Chemotherapy induces feedback up-regulation of CD44v6 in colorectal cancer initiating cells through ß-catenin/MDR1 signaling to sustain chemoresistance.

Ghatak, Shibnath; Hascall, Vincent C; Karamanos, Nikos; Markwald, Roger R; Misra, Suniti.

Afiliação

Ghatak S; Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC, United States.
Hascall VC; Department Natural Sciences, Trident Technical College, North Charleston, SC, United States.
Karamanos N; Department of Biomedical Engineering/ND20, Cleveland Clinic, Cleveland, OH, United States.
Markwald RR; University of Patras, Matrix Pathobiology Res. Group, Department of Chemistry, Patras, Greece.
Misra S; Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC, United States.

Front Oncol ; 12: 906260, 2022.

Article em En | MEDLINE | ID: mdl-36330477

Palavras-chave

CD44v6; MDR1; WNT3A; cancer initiating cells (CICs); colon rectal cancer (CRC)

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Front Oncol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google