Epidemiology of pneumonia in hospitalized adults ≥18 years old in four districts of Ulaanbaatar, Mongolia, 2015-2019.
Lancet Reg Health West Pac
; 30: 100591, 2023 Jan.
Article
em En
| MEDLINE
| ID: mdl-36419739
ABSTRACT
Background:
Community-acquired pneumonia is a leading cause of morbidity and mortality among children and adults worldwide. Adult pneumonia surveillance remains limited in many low- and middle-income settings, resulting in the disease burden being largely unknown.Methods:
A retrospective cohort study was conducted by reviewing medical charts for respiratory admissions at four district hospitals in Ulaanbaatar during January 2015-February 2019. Characteristics of community-acquired pneumonia cases were summarized by disease severity and age. To explore factors associated with severe pneumonia, we ran univariable and age-adjusted logistic regression models. Incidence rates were calculated using population denominators.Results:
In total, 4290 respiratory admissions met the case definition for clinical pneumonia, including 430 admissions of severe pneumonia. The highest proportion of severe pneumonia admissions occurred in adults >65 years (37.4%). After adjusting for age, there were increased odds of severe pneumonia in males (adjusted odds ratio [aOR] 1.63; 95% confidence interval [CI] 1.33-2.00) and those with ≥1 underlying medical condition (aOR 1.46; 95% CI 1.14-1.87). The incidence of hospitalized pneumonia in adults ≥18 years increased from 13.49 (95% CI 12.58-14.44) in 2015 to 17.65 (95% CI 16.63-18.71) in 2018 per 10,000 population. The incidence of severe pneumonia was highest in adults >65 years, ranging from 9.29 (95% CI 6.17-13.43) in 2015 to 12.69 (95% CI 9.22-17.04) in 2018 per 10,000 population. Interpretations Vaccination and other strategies to reduce the risk of pneumonia, particularly among older adults and those with underlying medical conditions, should be prioritized.Funding:
Pfizer clinical research collaboration agreement (contract number WI236621).
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Lancet Reg Health West Pac
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Austrália