miRNA-21, which disrupts metabolic reprogramming to facilitate CD4<sup>+</sup> T cell polarization toward the Th2 phenotype, accelerates arsenite-induced hepatic fibrosis.

Sun, Jing; Wu, Meng; Wang, Li; Wang, Peiwen; Xiao, Tian; Wang, Suhua; Liu, Qizhan

miRNA-21, which disrupts metabolic reprogramming to facilitate CD4⁺ T cell polarization toward the Th2 phenotype, accelerates arsenite-induced hepatic fibrosis.

Sun, Jing; Wu, Meng; Wang, Li; Wang, Peiwen; Xiao, Tian; Wang, Suhua; Liu, Qizhan.

Afiliação

Sun J; Center for Global Health, The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Suzhou Institute of Public Health, Gusu School, Nanjing Medical University, Nanjing 211166, Jiangsu, People's Republic of China; Department of Nutrition, Clinical Assessment Center of F
Wu M; Center for Global Health, The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Suzhou Institute of Public Health, Gusu School, Nanjing Medical University, Nanjing 211166, Jiangsu, People's Republic of China; Jiangsu Key Lab of Cancer Biomarkers, Prevention and Tre
Wang L; Department of Toxicology, School of Public Health, Baotou Medical College, Baotou 014040, Inner Mongolia, People's Republic of China.
Wang P; Center for Global Health, The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Suzhou Institute of Public Health, Gusu School, Nanjing Medical University, Nanjing 211166, Jiangsu, People's Republic of China; Jiangsu Key Lab of Cancer Biomarkers, Prevention and Tre
Xiao T; Center for Global Health, The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Suzhou Institute of Public Health, Gusu School, Nanjing Medical University, Nanjing 211166, Jiangsu, People's Republic of China; Jiangsu Key Lab of Cancer Biomarkers, Prevention and Tre
Wang S; Department of Toxicology, School of Public Health, Baotou Medical College, Baotou 014040, Inner Mongolia, People's Republic of China. Electronic address: bt_wangsuhua@163.com.
Liu Q; Center for Global Health, The Key Laboratory of Modern Toxicology, Ministry of Education, School of Public Health, Suzhou Institute of Public Health, Gusu School, Nanjing Medical University, Nanjing 211166, Jiangsu, People's Republic of China; Jiangsu Key Lab of Cancer Biomarkers, Prevention and Tre

Ecotoxicol Environ Saf ; 248: 114321, 2022 Dec 15.

Article em En | MEDLINE | ID: mdl-36427370

Assuntos

Arsênio; Arsenitos; MicroRNAs; Camundongos; Animais; Arsenitos/toxicidade; Interleucina-13; Interleucina-4; Fosfatidilinositol 3-Quinases/genética; Proteínas Proto-Oncogênicas c-akt/genética; Cirrose Hepática/induzido quimicamente; Fenótipo; Células Th2; MicroRNAs/genética

Palavras-chave

Arsenite; Glycolysis; Hepatic fibrosis; MiR-21; Th2 polarization

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arsênio / Arsenitos / MicroRNAs Limite: Animals Idioma: En Revista: Ecotoxicol Environ Saf Ano de publicação: 2022 Tipo de documento: Article

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