A Systems Analysis of Phenotype Heterogeneity in APOE*3Leiden.CETP Mice Induced by Long-Term High-Fat High-Cholesterol Diet Feeding.

Paalvast, Yared; Zhou, Enchen; Rozendaal, Yvonne J W; Wang, Yanan; Gerding, Albert; van Dijk, Theo H; de Boer, Jan Freark; Rensen, Patrick C N; van Dijk, Ko Willems; Kuivenhoven, Jan A; Bakker, Barbara M; van Riel, Natal A W; Groen, Albert K

Paalvast, Yared; Zhou, Enchen; Rozendaal, Yvonne J W; Wang, Yanan; Gerding, Albert; van Dijk, Theo H; de Boer, Jan Freark; Rensen, Patrick C N; van Dijk, Ko Willems; Kuivenhoven, Jan A; Bakker, Barbara M; van Riel, Natal A W; Groen, Albert K.

Afiliação

Paalvast Y; Department of Pediatrics, University of Groningen, University Medical Center Groningen, 9713 AV Groningen, The Netherlands.
Zhou E; Department of Medicine, Division of Endocrinology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Rozendaal YJW; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Wang Y; Department of Biomedical Engineering, Eindhoven University of Technology, 5600 MB Eindhoven, The Netherlands.
Gerding A; Department of Medicine, Division of Endocrinology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
van Dijk TH; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
de Boer JF; Department of Pediatrics, University of Groningen, University Medical Center Groningen, 9713 AV Groningen, The Netherlands.
Rensen PCN; Department of Pediatrics, University of Groningen, University Medical Center Groningen, 9713 AV Groningen, The Netherlands.
van Dijk KW; Department of Pediatrics, University of Groningen, University Medical Center Groningen, 9713 AV Groningen, The Netherlands.
Kuivenhoven JA; Department of Medicine, Division of Endocrinology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Bakker BM; Department of Biomedical Engineering, Eindhoven University of Technology, 5600 MB Eindhoven, The Netherlands.
van Riel NAW; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Groen AK; Department of Human Genetics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.

Nutrients ; 14(22)2022 Nov 21.

Article em En | MEDLINE | ID: mdl-36432620

Assuntos

Apolipoproteína E3; Proteínas de Transferência de Ésteres de Colesterol; Dieta Hiperlipídica; Síndrome Metabólica; Animais; Camundongos; Ácidos e Sais Biliares/metabolismo; Colesterol/metabolismo; Proteínas de Transferência de Ésteres de Colesterol/genética; Proteínas de Transferência de Ésteres de Colesterol/metabolismo; Dieta Hiperlipídica/efeitos adversos; Ácidos Graxos/metabolismo; Glucose/metabolismo; Fígado/metabolismo; Estudos Longitudinais; Síndrome Metabólica/genética; Síndrome Metabólica/metabolismo; Fenótipo; Análise de Sistemas; Triglicerídeos; Apolipoproteína E3/genética; Apolipoproteína E3/metabolismo

Palavras-chave

APOE3; CETP; bile acid; cholesterol; computational modeling; energy expenditure; metabolic syndrome; triglycerides

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome Metabólica / Proteínas de Transferência de Ésteres de Colesterol / Apolipoproteína E3 / Dieta Hiperlipídica Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Nutrients Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Holanda

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