Novel piperine-carboximidamide hybrids: design, synthesis, and antiproliferative activity via a multi-targeted inhibitory pathway.

Al-Wahaibi, Lamya H; Mahmoud, Mohamed A; Mostafa, Yaser A; Raslan, Ali E; Youssif, Bahaa G M

Al-Wahaibi, Lamya H; Mahmoud, Mohamed A; Mostafa, Yaser A; Raslan, Ali E; Youssif, Bahaa G M.

Afiliação

Al-Wahaibi LH; Department of Chemistry, College of Sciences, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Mahmoud MA; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut, Egypt.
Mostafa YA; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut, Egypt.
Raslan AE; Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Assiut, Egypt.
Youssif BGM; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut, Egypt.

J Enzyme Inhib Med Chem ; 38(1): 376-386, 2023 Dec.

Article em En | MEDLINE | ID: mdl-36453023

Assuntos

Alcamidas Poli-Insaturadas; Proteínas Proto-Oncogênicas B-raf; Benzodioxóis/farmacologia; Receptores ErbB

Palavras-chave

Piperine; amidoxime; antiproliferative; hybridisation; kinases

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas B-raf / Alcamidas Poli-Insaturadas Idioma: En Revista: J Enzyme Inhib Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Arábia Saudita

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