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Active DNA demethylation promotes cell fate specification and the DNA damage response.
Wang, Dongpeng; Wu, Wei; Callen, Elsa; Pavani, Raphael; Zolnerowich, Nicholas; Kodali, Srikanth; Zong, Dali; Wong, Nancy; Noriega, Santiago; Nathan, William J; Matos-Rodrigues, Gabriel; Chari, Raj; Kruhlak, Michael J; Livak, Ferenc; Ward, Michael; Caldecott, Keith; Di Stefano, Bruno; Nussenzweig, André.
Afiliação
  • Wang D; Laboratory of Genome Integrity, National Cancer Institute NIH, Bethesda, MD, USA.
  • Wu W; Laboratory of Genome Integrity, National Cancer Institute NIH, Bethesda, MD, USA.
  • Callen E; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China.
  • Pavani R; Laboratory of Genome Integrity, National Cancer Institute NIH, Bethesda, MD, USA.
  • Zolnerowich N; Laboratory of Genome Integrity, National Cancer Institute NIH, Bethesda, MD, USA.
  • Kodali S; Laboratory of Genome Integrity, National Cancer Institute NIH, Bethesda, MD, USA.
  • Zong D; Stem Cells and Regenerative Medicine, Center for Cell and Gene Therapy, Department of Molecular and Cellular Biology and Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA.
  • Wong N; Center for Cancer Epigenetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Noriega S; Laboratory of Genome Integrity, National Cancer Institute NIH, Bethesda, MD, USA.
  • Nathan WJ; Laboratory of Genome Integrity, National Cancer Institute NIH, Bethesda, MD, USA.
  • Matos-Rodrigues G; Laboratory of Genome Integrity, National Cancer Institute NIH, Bethesda, MD, USA.
  • Chari R; Laboratory of Genome Integrity, National Cancer Institute NIH, Bethesda, MD, USA.
  • Kruhlak MJ; Laboratory of Genome Integrity, National Cancer Institute NIH, Bethesda, MD, USA.
  • Livak F; Genome Modification Core, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
  • Ward M; Laboratory of Cancer Biology and Genetics, National Cancer Institute, NIH, Bethesda, MD, USA.
  • Caldecott K; Laboratory of Genome Integrity, National Cancer Institute NIH, Bethesda, MD, USA.
  • Di Stefano B; National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA.
  • Nussenzweig A; Genome Damage and Stability Centre, University of Sussex, Falmer Brighton, UK.
Science ; 378(6623): 983-989, 2022 12 02.
Article em En | MEDLINE | ID: mdl-36454826
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Elementos Facilitadores Genéticos / Timina DNA Glicosilase / Reparo do DNA / Quebras de DNA de Cadeia Simples / Células-Tronco Pluripotentes Induzidas / Desmetilação do DNA / Neurônios Limite: Humans Idioma: En Revista: Science Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Elementos Facilitadores Genéticos / Timina DNA Glicosilase / Reparo do DNA / Quebras de DNA de Cadeia Simples / Células-Tronco Pluripotentes Induzidas / Desmetilação do DNA / Neurônios Limite: Humans Idioma: En Revista: Science Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos