RNA biology: Alternative splicing hits synaptic function and behavior.

Kiebler, Michael A; Ninkovic, Jovica

Kiebler, Michael A; Ninkovic, Jovica.

Afiliação

Kiebler MA; Department of Anatomy and Cell Biology, Biomedical Center Munich (BMC), Faculty of Medicine, LMU, Munich, Germany. Electronic address: mkiebler@lmu.de.
Ninkovic J; Department of Anatomy and Cell Biology, Biomedical Center Munich (BMC), Faculty of Medicine, LMU, Munich, Germany; Institute of Stem Cell Research, Helmholtz Zentrum Munich, Munich, Germany.

Curr Biol ; 32(23): R1314-R1316, 2022 12 05.

Article em En | MEDLINE | ID: mdl-36473442

ABSTRACT

ABSTRACT

A new study finds the spliceosome protein SNRNP70 in cytoplasmic RNA granules in zebrafish motoneurons. Intriguingly, cytoplasmic SNRNP70 is essential for functional neuromuscular junctions, possibly due to a role in alternative splicing of z+agrin mRNA.

Assuntos

Processamento Alternativo; RNA; Animais; Peixe-Zebra/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA / Processamento Alternativo Limite: Animals Idioma: En Revista: Curr Biol Assunto da revista: BIOLOGIA Ano de publicação: 2022 Tipo de documento: Article

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