Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle.

Masania, Jinit; Wijten, Patrick; Keipert, Susanne; Ost, Mario; Klaus, Susanne; Rabbani, Naila; Thornalley, Paul J

Masania, Jinit; Wijten, Patrick; Keipert, Susanne; Ost, Mario; Klaus, Susanne; Rabbani, Naila; Thornalley, Paul J.

Afiliação

Masania J; Clinical Sciences Research Laboratories, Warwick Medical School, University of Warwick, University Hospital, Coventry, CV2 2DX, UK.
Wijten P; Diabetes Research Center, Qatar Biomedical Research Institute, Hamad Bin Khalifa University, Qatar Foundation, P.O. Box 34110, Doha, Qatar.
Keipert S; Department of Physiology of Energy Metabolism, German Institute of Human Nutrition, Potsdam-Rehbruecke, 14558, Nuthetal, Germany.
Ost M; Department of Physiology of Energy Metabolism, German Institute of Human Nutrition, Potsdam-Rehbruecke, 14558, Nuthetal, Germany.
Klaus S; Department of Physiology of Energy Metabolism, German Institute of Human Nutrition, Potsdam-Rehbruecke, 14558, Nuthetal, Germany; University of Potsdam, Institute of Nutrition Science, Potsdam-Rehbruecke, 14558, Nuthetal, Germany.
Rabbani N; Department of Basic Medical Science, College of Medicine, QU Health, Qatar University, P.O. Box 2713, Doha, Qatar.
Thornalley PJ; Clinical Sciences Research Laboratories, Warwick Medical School, University of Warwick, University Hospital, Coventry, CV2 2DX, UK; Diabetes Research Center, Qatar Biomedical Research Institute, Hamad Bin Khalifa University, Qatar Foundation, P.O. Box 34110, Doha, Qatar. Electronic address: pthornal

Redox Biol ; 59: 102574, 2023 02.

Article em En | MEDLINE | ID: mdl-36521306

Assuntos

Produtos Finais de Glicação Avançada; Envelhecimento Saudável; Humanos; Camundongos; Animais; Idoso; Lactente; Produtos Finais de Glicação Avançada/metabolismo; Lisina/metabolismo; Aldeído Pirúvico/metabolismo; Reação de Maillard; Proteína Desacopladora 1/metabolismo; Expressão Ectópica do Gene; Proteínas/metabolismo; Músculo Esquelético/metabolismo; Proteínas Supressoras de Tumor/metabolismo; Ubiquitina-Proteína Ligases/metabolismo

Palavras-chave

Aging; Methylglyoxal; Protein glycation; Proteomics; Skeletal muscle; Uncoupling protein 1

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Produtos Finais de Glicação Avançada / Envelhecimento Saudável Limite: Aged / Animals / Humans / Infant Idioma: En Revista: Redox Biol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido

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