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Computational design of peptides to target NaV1.7 channel with high potency and selectivity for the treatment of pain.
Nguyen, Phuong T; Nguyen, Hai M; Wagner, Karen M; Stewart, Robert G; Singh, Vikrant; Thapa, Parashar; Chen, Yi-Je; Lillya, Mark W; Ton, Anh Tuan; Kondo, Richard; Ghetti, Andre; Pennington, Michael W; Hammock, Bruce; Griffith, Theanne N; Sack, Jon T; Wulff, Heike; Yarov-Yarovoy, Vladimir.
Afiliação
  • Nguyen PT; Department of Physiology and Membrane Biology, University of California Davis, Davis, United States.
  • Nguyen HM; Department of Pharmacology, University of California Davis, Davis, United States.
  • Wagner KM; Department of Entomology and Nematology & Comprehensive Cancer Center, University of California Davis, Davis, United States.
  • Stewart RG; Department of Physiology and Membrane Biology, University of California Davis, Davis, United States.
  • Singh V; Department of Pharmacology, University of California Davis, Davis, United States.
  • Thapa P; Department of Physiology and Membrane Biology, University of California Davis, Davis, United States.
  • Chen YJ; Department of Pharmacology, University of California Davis, Davis, United States.
  • Lillya MW; Department of Physiology and Membrane Biology, University of California Davis, Davis, United States.
  • Ton AT; AnaBios Corporation, San Diego, United States.
  • Kondo R; AnaBios Corporation, San Diego, United States.
  • Ghetti A; AnaBios Corporation, San Diego, United States.
  • Pennington MW; Ambiopharm Inc, North Augusta, United States.
  • Hammock B; Department of Entomology and Nematology & Comprehensive Cancer Center, University of California Davis, Davis, United States.
  • Griffith TN; Department of Physiology and Membrane Biology, University of California Davis, Davis, United States.
  • Sack JT; Department of Physiology and Membrane Biology, University of California Davis, Davis, United States.
  • Wulff H; Department of Anesthesiology and Pain Medicine, University of California Davis, Davis, United States.
  • Yarov-Yarovoy V; Department of Pharmacology, University of California Davis, Davis, United States.
Elife ; 112022 12 28.
Article em En | MEDLINE | ID: mdl-36576241
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dor / Peptídeos / Canal de Sódio Disparado por Voltagem NAV1.7 / Bloqueadores do Canal de Sódio Disparado por Voltagem Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Elife Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dor / Peptídeos / Canal de Sódio Disparado por Voltagem NAV1.7 / Bloqueadores do Canal de Sódio Disparado por Voltagem Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Elife Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos