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The P2X7 receptor contributes to seizures and inflammation-driven long-lasting brain hyperexcitability following hypoxia in neonatal mice.
Smith, Jonathon; Menéndez Méndez, Aida; Alves, Mariana; Parras, Alberto; Conte, Giorgia; Bhattacharya, Anindya; Ceusters, Marc; Nicke, Annette; Henshall, David C; Jimenez-Mateos, Eva M; Engel, Tobias.
Afiliação
  • Smith J; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.
  • Menéndez Méndez A; FutureNeuro, SFI Research Centre for Chronic and Rare Neurological Diseases, RCSI University of Medicine and Health Sciences, Dublin, Ireland.
  • Alves M; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.
  • Parras A; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.
  • Conte G; Department of Biomedical Sciences, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
  • Bhattacharya A; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.
  • Ceusters M; Neuroimmunology Discover, Neuroscience, Janssen R&D, San Diego, California, USA.
  • Nicke A; Neuroscience Therapeutic Area, Janssen Research and Development, Janssen Pharmaceutica NV, Beerse, Belgium.
  • Henshall DC; The Marc Ceusters Company BV, Diest, Belgium.
  • Jimenez-Mateos EM; Walther Straub Institute of Pharmacology and Toxicology, Ludwig Maximilian University of Munich, Munich, Germany.
  • Engel T; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.
Br J Pharmacol ; 180(13): 1710-1729, 2023 07.
Article em En | MEDLINE | ID: mdl-36637008

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Convulsões / Receptores Purinérgicos P2X7 Limite: Animals Idioma: En Revista: Br J Pharmacol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Irlanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Convulsões / Receptores Purinérgicos P2X7 Limite: Animals Idioma: En Revista: Br J Pharmacol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Irlanda