Enhancer-instructed epigenetic landscape and chromatin compartmentalization dictate a primary antibody repertoire protective against specific bacterial pathogens.

Barajas-Mora, E Mauricio; Lee, Lindsay; Lu, Hanbin; Valderrama, J Andrés; Bjanes, Elisabet; Nizet, Victor; Feeney, Ann J; Hu, Ming; Murre, Cornelis

Barajas-Mora, E Mauricio; Lee, Lindsay; Lu, Hanbin; Valderrama, J Andrés; Bjanes, Elisabet; Nizet, Victor; Feeney, Ann J; Hu, Ming; Murre, Cornelis.

Afiliação

Barajas-Mora EM; Department of Molecular Biology, University of California, San Diego, La Jolla, CA, USA.
Lee L; Department of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.
Lu H; Department of Molecular Biology, University of California, San Diego, La Jolla, CA, USA.
Valderrama JA; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA.
Bjanes E; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA.
Nizet V; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA.
Feeney AJ; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, USA.
Hu M; Department of Immunology and Microbiology, Scripps Research, La Jolla, CA, USA.
Murre C; Department of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA. hum@ccf.org.

Nat Immunol ; 24(2): 320-336, 2023 02.

Article em En | MEDLINE | ID: mdl-36717722

Assuntos

Cromatina; Staphylococcus aureus Resistente à Meticilina; Camundongos; Animais; Cromatina/genética; Região Variável de Imunoglobulina/genética; Cadeias kappa de Imunoglobulina/genética; Staphylococcus aureus Resistente à Meticilina/genética; Linfócitos B; Epigênese Genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromatina / Staphylococcus aureus Resistente à Meticilina Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Nat Immunol Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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