Methionyl-tRNA synthetase of Escherichia coli. A zinc metalloprotein.
Biochim Biophys Acta
; 576(1): 128-33, 1979 Jan 25.
Article
em En
| MEDLINE
| ID: mdl-367445
ABSTRACT
The native dimeric form of methionyl-tRNA synthetase of Escherichia coli contains two zinc atoms per dimer, one per subunit. The bound zinc is retained upon trypsin modification which yields a monomer with one zinc atom. The enzymatic activity of both the dimeric forms is reversibly inhibited by 1,10-phenanthroline but not by its non-chelating analogues. In addition, the native enzyme binds two Mn2+ per dimer with a binding constant of approx. 70 micron but no binding is observed with the trypsin-modified monomer.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Escherichia coli
/
Aminoacil-tRNA Sintetases
/
Metionina tRNA Ligase
Idioma:
En
Revista:
Biochim Biophys Acta
Ano de publicação:
1979
Tipo de documento:
Article