SNPD-CRISPR: Single Nucleotide Polymorphism-Distinguishable Repression or Enhancement of a Target Gene Expression by CRISPR System.

Maruyama, Shohei; Kusakabe, Takashi; Zou, Xinyi; Kobayashi, Yoshiaki; Asano, Yoshimasa; Wang, Qingbo S; Ui-Tei, Kumiko

Maruyama, Shohei; Kusakabe, Takashi; Zou, Xinyi; Kobayashi, Yoshiaki; Asano, Yoshimasa; Wang, Qingbo S; Ui-Tei, Kumiko.

Afiliação

Maruyama S; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan.
Kusakabe T; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Zou X; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Kobayashi Y; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Asano Y; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.
Wang QS; Department of Statistical Genetics, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.
Ui-Tei K; Laboratory of Statistical Immunology, Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita, Osaka, Japan.

Methods Mol Biol ; 2637: 49-62, 2023.

Article em En | MEDLINE | ID: mdl-36773137

Assuntos

Sistemas CRISPR-Cas; Polimorfismo de Nucleotídeo Único; Sistemas CRISPR-Cas/genética; RNA/genética; Nucleotídeos; Expressão Gênica

Palavras-chave

HRAS; KRAB; PAM; SNPD-CRISPR; Seed region; Single nucleotide mutation; VP64; dCas9

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo de Nucleotídeo Único / Sistemas CRISPR-Cas Idioma: En Revista: Methods Mol Biol Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão

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