Calcitonin gene-related peptide and its receptor plays important role in nociceptive regulation in the arcuate nucleus of hypothalamus of rats with inflammatory pain.

Luo, Laixi; Qi, Wentao; Zhang, Yuyan; Wang, Jingyi; Guo, Li; Wang, Milin; Wang, Hong-Bo; Yu, Long-Chuan

Luo, Laixi; Qi, Wentao; Zhang, Yuyan; Wang, Jingyi; Guo, Li; Wang, Milin; Wang, Hong-Bo; Yu, Long-Chuan.

Afiliação

Luo L; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai 264005, PR China. Electronic address:
Qi W; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai 264005, PR China. Electronic address:
Zhang Y; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai 264005, PR China. Electronic address:
Wang J; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai 264005, PR China. Electronic address:
Guo L; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai 264005, PR China. Electronic address:
Wang M; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai 264005, PR China. Electronic address:
Wang HB; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai 264005, PR China. Electronic address:
Yu LC; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai 264005, PR China; Neurobiology Labora

Behav Brain Res ; 443: 114351, 2023 04 12.

Article em En | MEDLINE | ID: mdl-36804439

Assuntos

Peptídeo Relacionado com Gene de Calcitonina; Receptores de Peptídeo Relacionado com o Gene de Calcitonina; Animais; Ratos; Analgésicos/efeitos adversos; Núcleo Arqueado do Hipotálamo/metabolismo; Peptídeo Relacionado com Gene de Calcitonina/metabolismo; Peptídeo Relacionado com Gene de Calcitonina/farmacologia; Nociceptividade; Dor/metabolismo; Receptores de Peptídeo Relacionado com o Gene de Calcitonina/metabolismo

Palavras-chave

Antinociception; Arcuate nucleus (ARC); Calcitonin gene-related peptide (CGRP); Calcitonin receptor-like receptor (CLR); Knockdown CLR; Small interfering RNA (siRNA)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeo Relacionado com Gene de Calcitonina / Receptores de Peptídeo Relacionado com o Gene de Calcitonina Limite: Animals Idioma: En Revista: Behav Brain Res Ano de publicação: 2023 Tipo de documento: Article

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