Dermatopathologic features of cutaneous squamous cell carcinoma and actinic keratosis: Consensus criteria and proposed reporting guidelines.
J Am Acad Dermatol
; 88(6): 1317-1325, 2023 06.
Article
em En
| MEDLINE
| ID: mdl-36841336
ABSTRACT
BACKGROUND:
There is considerable variation in the literature regarding the dermatopathologic diagnostic features of and reporting guidelines for actinic keratosis (AK) and cutaneous squamous cell carcinoma (cSCC).OBJECTIVE:
To develop consensus recommendations regarding diagnostic criteria, nomenclature, and reporting of AK and cSCC.METHODS:
Literature review and cross-sectional multiround Delphi process including an international group of expert dermatopathologists followed by a consensus meeting.RESULTS:
Consensus was achieved regarding the key dermatopathologic features necessary for diagnosing cSCC, AK, and associated variants; grading of degree of cellular differentiation in cSCC; utility of immunohistochemistry for diagnosis of cSCC; and pathologic features that should be reported for cSCC and AK.LIMITATIONS:
Consensus was not achieved on all questions considered.CONCLUSION:
Despite the lack of clarity in the literature, there is consensus among expert dermatopathologists regarding diagnostic criteria and appropriate reporting of AK and cSCC. Widespread implementation of these consensus recommendations may improve communication between dermatopathologists and clinicians, facilitating appropriate treatment of AK and cSCC.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Cutâneas
/
Carcinoma de Células Escamosas
/
Ceratose Actínica
Tipo de estudo:
Diagnostic_studies
/
Guideline
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
J Am Acad Dermatol
Ano de publicação:
2023
Tipo de documento:
Article