Engineering protein glycosylation in CHO cells to be highly similar to murine host cells.

Gupta, Shivani; Shah, Bhavana; Fung, Coral Shek; Chan, Pik Kay; Wakefield, Devin L; Kuhns, Scott; Goudar, Chetan T; Piret, James M

Gupta, Shivani; Shah, Bhavana; Fung, Coral Shek; Chan, Pik Kay; Wakefield, Devin L; Kuhns, Scott; Goudar, Chetan T; Piret, James M.

Afiliação

Gupta S; Amgen, Inc., San Francisco, CA, United States.
Shah B; Michael Smith Laboratories, and Department of Chemical and Biological Engineering, University of British Columbia, Vancouver, BC, Canada.
Fung CS; Amgen, Inc., Thousand Oaks, CA, United States.
Chan PK; Amgen, Inc., Cambridge, MA, United States.
Wakefield DL; Amgen, Inc., Thousand Oaks, CA, United States.
Kuhns S; Amgen, Inc., San Francisco, CA, United States.
Goudar CT; Amgen, Inc., Thousand Oaks, CA, United States.
Piret JM; Amgen, Inc., Thousand Oaks, CA, United States.

Front Bioeng Biotechnol ; 11: 1113994, 2023.

Article em En | MEDLINE | ID: mdl-36873370

Palavras-chave

Chinese Hamster ovary (CHO); biosimilar; cell line engineering; glycosylation; murine

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Front Bioeng Biotechnol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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