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Decreased Paneth cell α-defensins promote fibrosis in a choline-deficient L-amino acid-defined high-fat diet-induced mouse model of nonalcoholic steatohepatitis via disrupting intestinal microbiota.
Nakamura, Shunta; Nakamura, Kiminori; Yokoi, Yuki; Shimizu, Yu; Ohira, Shuya; Hagiwara, Mizu; Song, Zihao; Gan, Li; Aizawa, Tomoyasu; Hashimoto, Daigo; Teshima, Takanori; Ouellette, Andre J; Ayabe, Tokiyoshi.
Afiliação
  • Nakamura S; Graduate School of Life Science, Hokkaido University, Sapporo, Japan.
  • Nakamura K; Hokkaido Laboratory, Corporate Research & Development Division, Nitto Denko Corporation, Sapporo, Japan.
  • Yokoi Y; Graduate School of Life Science, Hokkaido University, Sapporo, Japan. kiminori@sci.hokudai.ac.jp.
  • Shimizu Y; Department of Cell Biological Science, Faculty of Advanced Life Science, Hokkaido University, Kita-21, Nishi-11, Kita-ku, Sapporo, Hokkaido, 001-0021, Japan. kiminori@sci.hokudai.ac.jp.
  • Ohira S; Graduate School of Life Science, Hokkaido University, Sapporo, Japan.
  • Hagiwara M; Department of Cell Biological Science, Faculty of Advanced Life Science, Hokkaido University, Kita-21, Nishi-11, Kita-ku, Sapporo, Hokkaido, 001-0021, Japan.
  • Song Z; Department of Cell Biological Science, Faculty of Advanced Life Science, Hokkaido University, Kita-21, Nishi-11, Kita-ku, Sapporo, Hokkaido, 001-0021, Japan.
  • Gan L; Graduate School of Life Science, Hokkaido University, Sapporo, Japan.
  • Aizawa T; Graduate School of Life Science, Hokkaido University, Sapporo, Japan.
  • Hashimoto D; Graduate School of Life Science, Hokkaido University, Sapporo, Japan.
  • Teshima T; Graduate School of Life Science, Hokkaido University, Sapporo, Japan.
  • Ouellette AJ; Graduate School of Life Science, Hokkaido University, Sapporo, Japan.
  • Ayabe T; Department of Advanced Transdisciplinary Science, Faculty of Advanced Life Science, Hokkaido University, Sapporo, Japan.
Sci Rep ; 13(1): 3953, 2023 03 09.
Article em En | MEDLINE | ID: mdl-36894646
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Alfa-Defensinas / Hepatopatia Gordurosa não Alcoólica / Microbioma Gastrointestinal Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Alfa-Defensinas / Hepatopatia Gordurosa não Alcoólica / Microbioma Gastrointestinal Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão