Modeling incomplete penetrance in arrhythmogenic cardiomyopathy by human induced pluripotent stem cell derived cardiomyocytes.
Comput Struct Biotechnol J
; 21: 1759-1773, 2023.
Article
em En
| MEDLINE
| ID: mdl-36915380
ABC, active ß-catenin; ACM, arrhythmogenic cardiomyopathy; ASY, asymptomatic; Arrhythmogenic cardiomyopathy; BBB, bundle-branch block; CMs, cardiomyocytes; CTR, control; Cx43, connexin-43; DEGs, differentially expressed genes; GATK, Genome Analysis Toolkit; Human induced pluripotent stem cell derived cardiomyocytes; ICD, implantable cardioverter-defibrillator; ID, intercalated disk; Incomplete penetrance; LBB, left bundle-branch block; MRI, magnetic resonance imagingmut, mutated; NSVT, non-sustained ventricular tachycardia; RV, right ventricle; hiPSC, human induced pluripotent stem cell; wt, wild type
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Prognostic_studies
Idioma:
En
Revista:
Comput Struct Biotechnol J
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Itália