A combinatorial approach to uncover an additional Integrator subunit.

Offley, Sarah R; Pfleiderer, Moritz M; Zucco, Avery; Fraudeau, Angelique; Welsh, Sarah A; Razew, Michal; Galej, Wojciech P; Gardini, Alessandro

Offley, Sarah R; Pfleiderer, Moritz M; Zucco, Avery; Fraudeau, Angelique; Welsh, Sarah A; Razew, Michal; Galej, Wojciech P; Gardini, Alessandro.

Afiliação

Offley SR; The Wistar Institute, Philadelphia, PA 19103, USA; Cell and Molecular Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Pfleiderer MM; European Molecular Biology Laboratory, 71 Avenue des Martyrs, 38042 Grenoble, France.
Zucco A; The Wistar Institute, Philadelphia, PA 19103, USA.
Fraudeau A; European Molecular Biology Laboratory, 71 Avenue des Martyrs, 38042 Grenoble, France.
Welsh SA; The Wistar Institute, Philadelphia, PA 19103, USA.
Razew M; European Molecular Biology Laboratory, 71 Avenue des Martyrs, 38042 Grenoble, France.
Galej WP; European Molecular Biology Laboratory, 71 Avenue des Martyrs, 38042 Grenoble, France. Electronic address: wgalej@embl.fr.
Gardini A; The Wistar Institute, Philadelphia, PA 19103, USA. Electronic address: agardini@wistar.org.

Cell Rep ; 42(3): 112244, 2023 03 28.

Article em En | MEDLINE | ID: mdl-36920904

Assuntos

RNA Polimerase II; Transcrição Gênica; RNA Polimerase II/metabolismo

Palavras-chave

AlphaFold2; CP: Neuroscience; Integrator complex; RNA polymerase II; RNA polymerase II pausing; large protein complexes; molecular modeling; omics; pause-release; transcription; transcription factors; transcriptional regulation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transcrição Gênica / RNA Polimerase II Tipo de estudo: Prognostic_studies Idioma: En Revista: Cell Rep Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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