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Single-cell resolution reveals RalA GTPase expanding hematopoietic stem cells and facilitating of BCR-ABL1-driven leukemogenesis in a CRISPR/Cas9 gene editing mouse model.
Yin, Zhao; Su, Rui; Ge, Lanlan; Wang, Xiuyuan; Yang, Juhua; Huang, Guiping; Li, Chuting; Liu, Yanjun; Zhang, Keda; Deng, Lan; Fei, Jia.
Afiliação
  • Yin Z; Department of Biochemistry and Molecular Biology, Medical College of Jinan University, Guangzhou 510632, China.
  • Su R; Department of Hematology, Guangdong Second Provincial General Hospital, Jinan university, Guangzhou 510317, China.
  • Ge L; Guangdong Engineering Technology Research Center of Drug Development for Small Nucleic Acids, Guangzhou, China.
  • Wang X; Guangzhou Antisense Biopharmaceutical Technology Co., Ltd., Guangzhou 510632, China.
  • Yang J; Department of Biochemistry and Molecular Biology, Medical College of Jinan University, Guangzhou 510632, China.
  • Huang G; Guangdong Engineering Technology Research Center of Drug Development for Small Nucleic Acids, Guangzhou, China.
  • Li C; Guangzhou Antisense Biopharmaceutical Technology Co., Ltd., Guangzhou 510632, China.
  • Liu Y; Center Lab of Longhua Branch and Department of Infectious Disease, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University), Shenzhen, Guangdong 518020, China.
  • Zhang K; Department of pathology (Longhua Branch), Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University), Shenzhen, Guangdong 518020, China.
  • Deng L; Department of Biochemistry and Molecular Biology, Medical College of Jinan University, Guangzhou 510632, China.
  • Fei J; Guangdong Engineering Technology Research Center of Drug Development for Small Nucleic Acids, Guangzhou, China.
Int J Biol Sci ; 19(4): 1211-1227, 2023.
Article em En | MEDLINE | ID: mdl-36923939
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mielogênica Crônica BCR-ABL Positiva / Sistemas CRISPR-Cas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Int J Biol Sci Assunto da revista: BIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mielogênica Crônica BCR-ABL Positiva / Sistemas CRISPR-Cas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Int J Biol Sci Assunto da revista: BIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China