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Tacrolimus induces fibroblast-to-myofibroblast transition via a TGF-ß-dependent mechanism to contribute to renal fibrosis.
Ume, Adaku C; Wenegieme, Tara Y; Shelby, Jennae N; Paul-Onyia, Chiagozie D B; Waite, Aston M J; Kamau, John K; Adams, Danielle N; Susuki, Keiichiro; Bennett, Eric S; Ren, Hongmei; Williams, Clintoria R.
Afiliação
  • Ume AC; Department of Neuroscience, Cell Biology, and Physiology, Boonshoft School of Medicine and College of Science and Mathematics, Wright State University, Dayton, Ohio, United States.
  • Wenegieme TY; Department of Neuroscience, Cell Biology, and Physiology, Boonshoft School of Medicine and College of Science and Mathematics, Wright State University, Dayton, Ohio, United States.
  • Shelby JN; Department of Neuroscience, Cell Biology, and Physiology, Boonshoft School of Medicine and College of Science and Mathematics, Wright State University, Dayton, Ohio, United States.
  • Paul-Onyia CDB; Department of Neuroscience, Cell Biology, and Physiology, Boonshoft School of Medicine and College of Science and Mathematics, Wright State University, Dayton, Ohio, United States.
  • Waite AMJ; Department of Neuroscience, Cell Biology, and Physiology, Boonshoft School of Medicine and College of Science and Mathematics, Wright State University, Dayton, Ohio, United States.
  • Kamau JK; Department of Biochemistry and Molecular Biology, Boonshoft School of Medicine and College of Science and Mathematics, Wright State University, Dayton, Ohio, United States.
  • Adams DN; Department of Neuroscience, Cell Biology, and Physiology, Boonshoft School of Medicine and College of Science and Mathematics, Wright State University, Dayton, Ohio, United States.
  • Susuki K; Department of Neuroscience, Cell Biology, and Physiology, Boonshoft School of Medicine and College of Science and Mathematics, Wright State University, Dayton, Ohio, United States.
  • Bennett ES; Department of Neuroscience, Cell Biology, and Physiology, Boonshoft School of Medicine and College of Science and Mathematics, Wright State University, Dayton, Ohio, United States.
  • Ren H; Department of Biochemistry and Molecular Biology, Boonshoft School of Medicine and College of Science and Mathematics, Wright State University, Dayton, Ohio, United States.
  • Williams CR; Department of Biochemistry and Molecular Biology, Boonshoft School of Medicine and College of Science and Mathematics, Wright State University, Dayton, Ohio, United States.
Am J Physiol Renal Physiol ; 324(5): F433-F445, 2023 05 01.
Article em En | MEDLINE | ID: mdl-36927118
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tacrolimo / Insuficiência Renal / Fator de Crescimento Transformador beta1 / Miofibroblastos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Am J Physiol Renal Physiol Assunto da revista: FISIOLOGIA / NEFROLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tacrolimo / Insuficiência Renal / Fator de Crescimento Transformador beta1 / Miofibroblastos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Am J Physiol Renal Physiol Assunto da revista: FISIOLOGIA / NEFROLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos