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Stretchable, flexible and breathable polylactic acid/polyvinyl pyrrolidone bandage based on Kirigami for wounds monitoring and treatment.
Xu, Lei; Ding, Liqiang; Sun, Yuehua; Zhang, Tong; Zhu, Youfu; Yan, Bingyu; Yang, Min; Ramakrishna, Seeram; Zhang, Jun; Long, Yun-Ze.
Afiliação
  • Xu L; Collaborative Innovation Center for Nanomaterials & Devices, College of Physics, Qingdao University, Qingdao 266071, PR China.
  • Ding L; Collaborative Innovation Center for Nanomaterials & Devices, College of Physics, Qingdao University, Qingdao 266071, PR China.
  • Sun Y; Collaborative Innovation Center for Nanomaterials & Devices, College of Physics, Qingdao University, Qingdao 266071, PR China.
  • Zhang T; Collaborative Innovation Center for Nanomaterials & Devices, College of Physics, Qingdao University, Qingdao 266071, PR China.
  • Zhu Y; The Affiliated Hospital of Qingdao University, Qingdao 266000, China.
  • Yan B; Collaborative Innovation Center for Nanomaterials & Devices, College of Physics, Qingdao University, Qingdao 266071, PR China.
  • Yang M; Collaborative Innovation Center for Nanomaterials & Devices, College of Physics, Qingdao University, Qingdao 266071, PR China; School of Mechanical and Automotive Engineering, Qingdao University of Technology, Qingdao 266520, China.
  • Ramakrishna S; Center for Nanofibers & Nanotechnology, Department of Mechanical Engineering, National University of Singapore, Singapore 117574, Singapore.
  • Zhang J; Collaborative Innovation Center for Nanomaterials & Devices, College of Physics, Qingdao University, Qingdao 266071, PR China. Electronic address: iamjunzhang@163.com.
  • Long YZ; Collaborative Innovation Center for Nanomaterials & Devices, College of Physics, Qingdao University, Qingdao 266071, PR China. Electronic address: yunze.long@qdu.edu.cn.
Int J Biol Macromol ; 237: 124204, 2023 May 15.
Article em En | MEDLINE | ID: mdl-36990399
Chronic wounds are slow to recover. During treatment, the dressing needs to be removed to check the recovery status, a process that often results in wound tears. Traditional dressings lack stretching and flexing properties and are not suitable using on wounds in joints, which require movement from time to time. In this study, we present a stretchable, flexible and breathable bandage consisting of three layers, including Mxene coating on the top, the polylactic acid/polyvinyl pyrrolidone (PLA/PVP) layer designed as Kirigami in the middle, and the f-sensor at the bottom. By the way, the f-sensor is in contact with the wound sensing real-time microenvironmental changes due to infection. When the infection intensifies, the Mxene coating at the top is utilized to enable anti-infection treatment. And Kirigami structure of PLA/PVP ensures that this bandage has stretchability, bendability, and breathability. The stretch of the smart bandage increases to 831 % compared to the original structure, and the modulus reduces to 0.04 %, which adapts extremely well to the movement of the joints and relieves the pressure on the wound. This monitoring-treatment closed-loop working mode, eliminating the need to remove dressings and avoid tissue tearing, shows a promising capability in the field of surgical wound care.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polivinil / Povidona Idioma: En Revista: Int J Biol Macromol Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polivinil / Povidona Idioma: En Revista: Int J Biol Macromol Ano de publicação: 2023 Tipo de documento: Article