Constitutive and conditional gene knockout mice for the study of intervertebral disc degeneration: Current status, decision considerations, and future possibilities.

Lu, Ze-Yu; Chen, Peng-Bo; Xu, Qing-Yin; Li, Bo; Jiang, Sheng-Dan; Jiang, Lei-Sheng; Zheng, Xin-Feng

Lu, Ze-Yu; Chen, Peng-Bo; Xu, Qing-Yin; Li, Bo; Jiang, Sheng-Dan; Jiang, Lei-Sheng; Zheng, Xin-Feng.

Afiliação

Lu ZY; Spine Center Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Shanghai China.
Chen PB; Spine Center Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Shanghai China.
Xu QY; Spine Center Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Shanghai China.
Li B; Spine Center Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Shanghai China.
Jiang SD; Spine Center Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Shanghai China.
Jiang LS; Spine Center Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Shanghai China.
Zheng XF; Spine Center Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Shanghai China.

JOR Spine ; 6(1): e1242, 2023 Mar.

Article em En | MEDLINE | ID: mdl-36994464

Palavras-chave

construction; gene edition technology; gene targeting; guideline; intervertebral disc degeneration; knockout; mouse model; specific Cre recombinase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: JOR Spine Ano de publicação: 2023 Tipo de documento: Article

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