Loss of Ezh2 function remodels the DNA replication initiation landscape.

Prorok, Paulina; Forouzanfar, Faezeh; Murugarren, Nerea; Peiffer, Isabelle; Charton, Romain; Akerman, Ildem; Méchali, Marcel

Prorok, Paulina; Forouzanfar, Faezeh; Murugarren, Nerea; Peiffer, Isabelle; Charton, Romain; Akerman, Ildem; Méchali, Marcel.

Afiliação

Prorok P; Institute of Human Genetics, CNRS-University of Montpellier, Montpellier 34090, France. Electronic address: paulina.prorok@tu-darmstadt.de.
Forouzanfar F; Institute of Human Genetics, CNRS-University of Montpellier, Montpellier 34090, France.
Murugarren N; Institute of Metabolism and Systems Research (IMSR), University of Birmingham, Birmingham B152TT, UK; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham B152TT, UK.
Peiffer I; Institute of Human Genetics, CNRS-University of Montpellier, Montpellier 34090, France.
Charton R; Institute of Human Genetics, CNRS-University of Montpellier, Montpellier 34090, France.
Akerman I; Institute of Metabolism and Systems Research (IMSR), University of Birmingham, Birmingham B152TT, UK; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham B152TT, UK. Electronic address: i.akerman@bham.ac.uk.
Méchali M; Institute of Human Genetics, CNRS-University of Montpellier, Montpellier 34090, France. Electronic address: marcel.mechali@igh.cnrs.fr.

Cell Rep ; 42(4): 112280, 2023 04 25.

Article em En | MEDLINE | ID: mdl-36995935

Assuntos

Proteína Potenciadora do Homólogo 2 de Zeste; Histonas; Animais; Histonas/metabolismo; Proteína Potenciadora do Homólogo 2 de Zeste/genética; Proteína Potenciadora do Homólogo 2 de Zeste/metabolismo; Complexo Repressor Polycomb 2/genética; Complexo Repressor Polycomb 2/metabolismo; Cromatina; Replicação do DNA/genética; DNA

Palavras-chave

CP: Molecular biology; DNA replication initiation; DNA replication origins; EZH2 knockout; H3K27me3; PRC2; SNS-seq; bivalent promoters; chromatin; polycomb

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Histonas / Proteína Potenciadora do Homólogo 2 de Zeste Limite: Animals Idioma: En Revista: Cell Rep Ano de publicação: 2023 Tipo de documento: Article

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