The correlation between prenatal maternal active smoking and neurodevelopmental disorders in children: a systematic review and meta-analysis.
BMC Public Health
; 23(1): 611, 2023 03 30.
Article
em En
| MEDLINE
| ID: mdl-36997899
ABSTRACT
OBJECTIVE:
To systematically evaluate the association between maternal active smoking during pregnancy and Tourette syndrome (TS), chronic tic disorder (CTD), and developmental coordination disorder (DCD) in children, and to provide evidence-based medical references to reduce the incidence of neurodevelopmental disorders in children.METHOD:
We searched PubMed, Web of Science, Embase, and Cochrane Library to obtain relevant articles published before 4 August 2021. Two reviewers independently assessed the articles for eligibility and extracted data.RESULTS:
We included eight studies involving a total of 50,317 participants (3 cohort, 3 case-control, and 2 cross-sectional studies). The pooled effect estimates suggested that prenatal maternal active smoking is related to an increased risk of neurodevelopmental disorders (OR = 1.91, 95% CI 1.30-2.80), especially DCD (OR = 2.25, 95% CI 1.35-3.75). Maternal active smoking during pregnancy is not associated with TS (OR = 1.07, 95% CI 0.66-1.73) in children.CONCLUSION:
In this meta-analysis, we found evidence for a correlation between active smoking exposure in pregnant women and neurodevelopmental disorders in children. Owing to the differences in sample size, smoking categories and diagnostic methods, further research is needed to validate our results.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fumar
/
Transtornos do Neurodesenvolvimento
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
/
Systematic_reviews
Limite:
Child
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Female
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Humans
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Pregnancy
Idioma:
En
Revista:
BMC Public Health
Assunto da revista:
SAUDE PUBLICA
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
China