Protein Kinase CK2 Promotes Proliferation, Abnormal Differentiation, and Proinflammatory Cytokine Production of Keratinocytes via Regulation of STAT3 and Akt Pathways in Psoriasis.

Huang, Wenjie; Zheng, Xuyu; Huang, Qi; Weng, Danlin; Yao, Shifei; Zhou, Cui; Li, Qian; Hu, Yulian; Xu, Wenchun; Huang, Kun

Huang, Wenjie; Zheng, Xuyu; Huang, Qi; Weng, Danlin; Yao, Shifei; Zhou, Cui; Li, Qian; Hu, Yulian; Xu, Wenchun; Huang, Kun.

Afiliação

Huang W; Key Laboratory of Diagnostic Medicine Designated by the Ministry of Education, Chongqing Medical University, Chongqing, China.
Zheng X; Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Huang Q; Key Laboratory of Diagnostic Medicine Designated by the Ministry of Education, Chongqing Medical University, Chongqing, China.
Weng D; Key Laboratory of Diagnostic Medicine Designated by the Ministry of Education, Chongqing Medical University, Chongqing, China.
Yao S; Key Laboratory of Diagnostic Medicine Designated by the Ministry of Education, Chongqing Medical University, Chongqing, China.
Zhou C; Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Li Q; Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Hu Y; Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xu W; Key Laboratory of Diagnostic Medicine Designated by the Ministry of Education, Chongqing Medical University, Chongqing, China.
Huang K; Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Electronic address: feelingkun@126.com.

Am J Pathol ; 193(5): 567-578, 2023 05.

Article em En | MEDLINE | ID: mdl-37080661

Assuntos

Proteínas Proto-Oncogênicas c-akt; Psoríase; Animais; Humanos; Camundongos; Caseína Quinase II/metabolismo; Diferenciação Celular; Proliferação de Células; Citocinas/metabolismo; Imiquimode/efeitos adversos; Interleucina-17/metabolismo; Queratinócitos/patologia; Camundongos Endogâmicos BALB C; Proteínas Proto-Oncogênicas c-akt/metabolismo; Psoríase/induzido quimicamente; Pele/metabolismo; Fator de Transcrição STAT3/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Psoríase / Proteínas Proto-Oncogênicas c-akt Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Am J Pathol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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