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Diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a refined classification from the European society for blood and marrow transplantation (EBMT).
Mohty, Mohamad; Malard, Florent; Alaskar, Ahmed S; Aljurf, Mahmoud; Arat, Mutlu; Bader, Peter; Baron, Frederic; Bazarbachi, Ali; Blaise, Didier; Brissot, Eolia; Ciceri, Fabio; Corbacioglu, Selim; Dalle, Jean-Hugues; Dignan, Fiona; Huynh, Anne; Kenyon, Michelle; Nagler, Arnon; Pagliuca, Antonio; Peric, Zinaida; Richardson, Paul G; Ruggeri, Annalisa; Ruutu, Tapani; Yakoub-Agha, Ibrahim; Duarte, Rafael F; Carreras, Enric.
Afiliação
  • Mohty M; Hematology Department, Hôpital Saint-Antoine, and Université Pierre & Marie Curie, Paris, France. mohamad.mohty@inserm.fr.
  • Malard F; Hematology Department, Hôpital Saint-Antoine, and Université Pierre & Marie Curie, Paris, France.
  • Alaskar AS; King Abdullah International Medical Research Center/King Saud Bin Abdulaziz University for Health Sciences, Dept. of Oncology, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.
  • Aljurf M; King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
  • Arat M; Sisli Florence Nightingale Hospital, HSCT Unit, Istanbul, Turkey.
  • Bader P; Division for Stem Cell Transplantation and Immunology, Department for Children and Adolescents, University Hospital, Goethe University, Frankfurt/Main, Germany.
  • Baron F; Department of Hematology, University of Liege, Liege, Belgium.
  • Bazarbachi A; Department of Internal Medicine, American University of Beirut, Beirut, Lebanon.
  • Blaise D; Aix-Marseille Univ, MSC Lab, Institut Paoli-Calmettes, Department of Hematology, Marseille, France.
  • Brissot E; Hematology Department, Hôpital Saint-Antoine, and Université Pierre & Marie Curie, Paris, France.
  • Ciceri F; San Raffaele Scientific Institute, Hematology and Bone marrow Transplantation Unit, Milan, Italy.
  • Corbacioglu S; Department of Pediatric Hematology, Oncology and Stem Cell Transplantation, University of Regensburg, Regensburg, Germany.
  • Dalle JH; Department of Hematology and Immunology, Hospital Robert Debre, Paris 7-Paris Diderot University, Paris, France.
  • Dignan F; Department of Clinical Haematology, Manchester University NHS Foundation Trust, Manchester, UK.
  • Huynh A; Hematology Department, Institut Universitaire du Cancer Toulouse - Oncopole, Toulouse, France.
  • Kenyon M; Department of Haematology, King's College Hospital, London, UK.
  • Nagler A; Hematology and Bone Marrow Transplantation, Chaim Sheba Medical center, Tel-Hashomer, Israel.
  • Pagliuca A; Department of Haematology, King's College Hospital, London, UK.
  • Peric Z; Department of Hematology, University Hospital Centre Zagreb and School of Medicine, University of Zagreb, Zagreb, Croatia.
  • Richardson PG; Division of Hematology, Mayo Clinic, Rochester, MN, USA.
  • Ruggeri A; San Raffaele Scientific Institute, Hematology and Bone marrow Transplantation Unit, Milan, Italy.
  • Ruutu T; Clinical Research Institute, Helsinki University Hospital, Helsinki, Finland.
  • Yakoub-Agha I; CHU de Lille, Univ Lille, INSERM U1286, Infinite, 59000, Lille, France.
  • Duarte RF; Department of Hematology, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.
  • Carreras E; Josep Carreras Foundation & Leukemia Research Institute, (Hospital Clínic/Barcelona University Campus), Barcelona, Spain.
Bone Marrow Transplant ; 58(7): 749-754, 2023 07.
Article em En | MEDLINE | ID: mdl-37095231
ABSTRACT
Sinusoidal obstruction syndrome, also known as veno-occlusive disease (SOS/VOD), is a potentially life-threatening complication that can develop after hematopoietic cell transplantation (HCT). A new definition for diagnosis, and a severity grading system for SOS/VOD in adult patients, was reported a few years ago on behalf of the European Society for Blood and Marrow Transplantation (EBMT). The aim of this work is to update knowledge regarding diagnosis and severity assessment of SOS/VOD in adult patients, and also its pathophysiology and treatment. In particular, we now propose to refine the previous classification and distinguish probable, clinical and proven SOS/VOD at diagnosis. We also provide an accurate definition of multiorgan dysfunction (MOD) for SOS/VOD severity grading based on Sequential Organ Failure Assessment (SOFA) score.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Vasculares / Hepatopatia Veno-Oclusiva / Transplante de Células-Tronco Hematopoéticas Tipo de estudo: Diagnostic_studies / Etiology_studies Limite: Adult / Humans Idioma: En Revista: Bone Marrow Transplant Assunto da revista: TRANSPLANTE Ano de publicação: 2023 Tipo de documento: Article País de afiliação: França

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Vasculares / Hepatopatia Veno-Oclusiva / Transplante de Células-Tronco Hematopoéticas Tipo de estudo: Diagnostic_studies / Etiology_studies Limite: Adult / Humans Idioma: En Revista: Bone Marrow Transplant Assunto da revista: TRANSPLANTE Ano de publicação: 2023 Tipo de documento: Article País de afiliação: França