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A highly selective purine-based inhibitor of CSF1R potently inhibits osteoclast differentiation.
Aarhus, Thomas Ihle; Eickhoff, Jan; Klebl, Bert; Unger, Anke; Boros, Joanna; Choidas, Axel; Zischinsky, Mia-Lisa; Wolowczyk, Camilla; Bjørkøy, Geir; Sundby, Eirik; Hoff, Bård Helge.
Afiliação
  • Aarhus TI; Department of Chemistry, Norwegian University of Science and Technology (NTNU), Høgskoleringen 5, NO-7491, Trondheim, Norway; Lead Discovery Center GmbH (LDC), Otto-Hahn-Strasse 15, 44227, Dortmund, Germany.
  • Eickhoff J; Lead Discovery Center GmbH (LDC), Otto-Hahn-Strasse 15, 44227, Dortmund, Germany.
  • Klebl B; Lead Discovery Center GmbH (LDC), Otto-Hahn-Strasse 15, 44227, Dortmund, Germany.
  • Unger A; Lead Discovery Center GmbH (LDC), Otto-Hahn-Strasse 15, 44227, Dortmund, Germany.
  • Boros J; Lead Discovery Center GmbH (LDC), Otto-Hahn-Strasse 15, 44227, Dortmund, Germany.
  • Choidas A; Lead Discovery Center GmbH (LDC), Otto-Hahn-Strasse 15, 44227, Dortmund, Germany.
  • Zischinsky ML; Lead Discovery Center GmbH (LDC), Otto-Hahn-Strasse 15, 44227, Dortmund, Germany.
  • Wolowczyk C; Department of Biomedical Laboratory Science, Norwegian University of Science and Technology (NTNU), NO-7491, Trondheim, Norway; Centre of Molecular Inflammation Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology (NTNU), NO-7491, Trondheim,
  • Bjørkøy G; Department of Biomedical Laboratory Science, Norwegian University of Science and Technology (NTNU), NO-7491, Trondheim, Norway; Centre of Molecular Inflammation Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology (NTNU), NO-7491, Trondheim,
  • Sundby E; Department of Material Science, Norwegian University of Science and Technology (NTNU), NO-7491, Trondheim, Norway.
  • Hoff BH; Department of Chemistry, Norwegian University of Science and Technology (NTNU), Høgskoleringen 5, NO-7491, Trondheim, Norway. Electronic address: bard.helge.hoff@chem.ntnu.
Eur J Med Chem ; 255: 115344, 2023 Jul 05.
Article em En | MEDLINE | ID: mdl-37141705
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoclastos / Macrófagos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Eur J Med Chem Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoclastos / Macrófagos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Eur J Med Chem Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha