Nasal administration of orexin A partially rescues dizocilpine-induced cognitive impairments in female C57BL/6 J mice.

Durairaja, Archana; Pandey, Samiksha; Kahl, Evelyn; Fendt, Markus

Nasal administration of orexin A partially rescues dizocilpine-induced cognitive impairments in female C57BL/6 J mice.

Durairaja, Archana; Pandey, Samiksha; Kahl, Evelyn; Fendt, Markus.

Afiliação

Durairaja A; Institute for Pharmacology and Toxicology, Otto-von-Guericke University, Magdeburg, Germany. Electronic address: archana.durairaja@med.ovgu.de.
Pandey S; Institute for Pharmacology and Toxicology, Otto-von-Guericke University, Magdeburg, Germany; Integrative Neuroscience Programme, Otto-von-Guericke University, Magdeburg, Germany.
Kahl E; Institute for Pharmacology and Toxicology, Otto-von-Guericke University, Magdeburg, Germany.
Fendt M; Institute for Pharmacology and Toxicology, Otto-von-Guericke University, Magdeburg, Germany; Center of Behavioral Brain Sciences, Otto-von-Guericke University, Magdeburg, Germany.

Behav Brain Res ; 450: 114491, 2023 07 26.

Article em En | MEDLINE | ID: mdl-37172740

Assuntos

Disfunção Cognitiva; Maleato de Dizocilpina; Humanos; Feminino; Camundongos; Masculino; Animais; Maleato de Dizocilpina/farmacologia; Orexinas/farmacologia; Antagonistas de Aminoácidos Excitatórios/farmacologia; Administração Intranasal; Camundongos Endogâmicos C57BL; Disfunção Cognitiva/induzido quimicamente; Disfunção Cognitiva/tratamento farmacológico

Palavras-chave

Cognition; Dizocilpine; Neuropsychiatric disorders; Orexin; Sex-difference; Visual discrimination

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Maleato de Dizocilpina / Disfunção Cognitiva Limite: Animals / Female / Humans / Male Idioma: En Revista: Behav Brain Res Ano de publicação: 2023 Tipo de documento: Article

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